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Title:

???????? ????? ??????? E0

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Title: Author: Kaufman Last modified by: Roy Glasberg Created Date: 12/9/2000 12:47:44 PM Document presentation format – PowerPoint PPT presentation

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Title: ???????? ????? ??????? E0


1
????????
???? X ???? ????? ??? ??? ?? ??????? ???????
????? ????.
????
?????
2
???????? ????? ??????? E0
  • ???? ??? ????? ??? ?? ???? ?????? ???? ???? ???.
  • ??? ???? ??? ?????? ?? ?? ????
  • ???? ????? ?? ????? ???? ??? E0 ?????
  • ???? ?????? ?? ????? ???? ??? E0 ?????.

3
?????? ???????? ??????? ??? ???????
  1. H ???? ??????? ?- -X, ????? ????? ????.
    ????? ???? ????? ?-H2
  2. X ???? ??????? ?-H2 ????? ????? ????, ??????
    ????? ?- -X

4
??? ??????? ?????? ?????????
5
???? ???????? ?? ???????? ?????
6
???? 2
??? ??
E0
DE0 -0.19 0.32V 0.13V
7
??????? ??????? ?? ???? DG0
  • ???? ????? ??? ??????? ??? ????????.
  • ???? ????? ??????? ????????? ??????

DG0 -nF DE0
F23.06 kcal/V mol
8
???? 3 ????? ????? 2 ????? ?? DG0
DE0 -0.19 0.32V 0.13V
9
DG0 -nFDE0-2 x 23.06 x 0.13 -6 kCal/mol
??????? ????????
10
???? ?????? ?????? ?????????? ?? ??????? ???????
11
????? 4
?. ??? ?????? ???? ????? ???????? ?
DGO -7.3 10.3 3kCal/mol
12
???? ??? ??? ???? ????? Creatine-P?
??? ??????? ???????
R1.98 cal/mol x ok T298oK
DG DG0 RTln
????? ?????? ??????? ????? ?? ?????? ?????????
??????-???? DG0, ????? ???? ?? Keq
13
????? 5
?. ???
?DGO
14
?. ???? ?? ???? ??? ATP ? ADP ??? 10. ?? ???? ???
?????? ???????????????? ?
3.27 x 104
15
Energy Charge
  • ???? ?? ?????? ??????? ?? ???.

?? ???? ??????? ????
ATP8OmM ADP8mM AMP9mM
0.78
16
????? ????????
  • ???? ??????? ??? ???? ?-DG0 ?? ??? ????????, ???
    ???? ?? ???? "?????????".

???????? ??? ?? ???? ????????
17
????? 3
PPi
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