Title: Ext.?????? ?.??????? Ext.???? ??????? Ext.????? ??????????
1Ext.?????? ?.??????? Ext.???? ???????Ext.?????
??????????
2????????????????
3????????????????
- Every two seconds,
- someone in the world suffers a strokeEvery six
seconds, - someone dies of a strokeEvery six seconds,
- someones quality of life will forever be
changed they will permanently be physically
disabled due to stroke
4????????????????
- ?????????????????????????????????????????????????
??????????????????????????????????????????????????
?? ??????????????????????????????????????????????
?.?. 2551 ???????????????????????????????????
257/100,000 ???????????? 980/100,000 ??
?????????????? 1,629 ????????? ?????????
257/100,000 ??(446/???) ?????????????? 29,571
????????? ???????????????? 2,973 ????????????
??????????????????????????????????? 0.5
?????????????????????????????? 20,632
???????????? ??????? ?.?. 2552 ???????????????????
?????????????21/100,000
5??????????????????????????????????????????????Dis
ability Adjusted Life Years (DALYs)
????????????? ?.?. 2542 (??????)
- ??? DALYs ??????
- 1. ????? 960,086 17
- 2. ??????????????? 510,909 9
- 3. ????????????? 271,009 5
- 4. ????????? 248,083 4
- 5. ??????? 168,594 3
- 6. ??????????????????????? 159,188 3
- 7. ??????????????? 156,861 3
- 8. ??????????/????????? 156,853 3
- 9. ?????????/???????????? 147,988 3
- 10. ???????? 137,703 2
- ????? Burden of disease and injuries in
Thailand Minstry of Public Health Nov 2002 - (http//203 157.19.191/index-burden.htm)
6??????????????????????????????????????????????
DALYs ????????????? ?.?. 2542 (???????)
- ??? DALYs ??????
- 1. ????? 372,956 10
- 2. ????????????? 282,509 7
- 3.. ??????? 267,155 7
- 4. ??????????? 145?336 4
- 5. ????????? 118,384 3
- 6. ????????????? 117,994 3
- 7. ????????(????????????) 112,990 3
- 8. ??????????????? 108,449 3
- 9. ??????????????????????? 102,863 3
- 10. ???????? 96,091 2
- ????? Burden of disease and injuries in
Thailand Minstry of Public Health Nov 2002 - (http//203 157.19.191/index-burden.htm)
7The top killers in Thailand 1999 (Male)
- Diseases Deaths
- 1. HIVAIDS 40,064 18
- 2. Traffic accidents 21,901 10
- 3. Stroke 18,286 8
- 4. Liver cancer 13,774 6
- 5. COPD 10,977 5
- 6. Ischemic heart disease 9,734 4
- 7. Homicide/Violence 6,786 3
- 8. Suicides 6,671 3
- 9. Lung cancer 6,461 3
- 10. Diabetes 6,223 3
- ????? Burden of disease and injuries in
Thailand Minstry of Public Health Nov 2002 - (http//203 157.19.191/index-burden.htm)
8Top 10 killers in Thailand 1999 (Female)
- Diseases Deaths
- 1. Stroke 23,433 14
- 2. HIVIAIDS 16,443 10
- 3. Diabetes 12,235 7
- 4. Ischemic heart disease 8,089 5
- 5. Liver cancer 7,938 3
- 6. Lower respiratory tract infection 5,521 3
- 7. Traffic accident 5,330 3
- 8. COPD 5,132 3
- 9. Tuberculosis 4,413 3
- 10. Nephritis Nephrosis 4,123 2
- ????? Burden of disease and injuries in
Thailand Minstry of Public Health Nov 2002 - (http//203 157.19.191/index-burden.htm)
9????????????????
- ????????????????????????????????????????????????
???????????????????????????? ???????????????
??????????????????????????????????????????????????
???????????????????????????????????????????????
??????????????????????????????????????????????????
??????????????????????????????????????????????????
????? ???????????????????????????????????????????
10????????????
- ??????????????????????????????????????????????
?.???????? - ?????????????????????????????????????????????????,
????, ?????????????????????????? - ??????????????????????????????????????????????????
????????????
11????????????
- ??????????????????????????????????????????????????
????????????????????(??????? HosXp)
?????????????????? ???????????????
??????????.?.2553-2556 - ?????????????????? SPSS
12- ?????????????????????
- ???
- ????
- ??????????????????????? Ischemic, Hemorrhagic,
Unknown - ???????????? DM, HT, DLP, Heart disease,
Smoking - ????????????
13????????????????
??. ??. ?????? ???????? ??????????????? ??????????
??? ?????????????????????
14????????????????
Cerebrovascular disease CVD (CVA) STROKE Brain
Attack
Rapidly developed clinical signs of
focal(global) disturbance of cerebral function
lasting more than 24 hours or leading to death,
with no apparent cause other than a vascular
origin.
15????? stroke
????????????
16STROKE ! !
- ?????????????????????????????????????
- ???????????? ????????
17????????????????
??????????? ???? ?????? STROKE , CEREBROVASCULAR
DISEASE (CVD)
??????????? 2 ???????? 1. ????????????????????
????????? (Ischemic stroke) 2.
??????????????????? (Hemorrhagic stroke)
18Types of Ischemic Stroke
19???????????????????
?????????????????????? ??????????????????????????
???????????????????????? ?????????????????????????
?????????????????????????????????????????????????
???????????????????????????
20??? ?????????????????????????????????????????? ?
21??????????????????????????????????????
- ??????????????????
- ??????????
- ????????????
- ????????
- ???????
- ???????????????
- ?????????
- ?????????????????
- ?????? (sleep apnea)
- ????
22Stroke Risk Factors
????????????????? Non-modifiableAge, Gender,
Race, Heredity
?????????????? Modifiable
- Behaviors
- Cigarette smoking
- Alcohol abuse
- Physical inactivity
- Medical Conditions
- Hypertension
- Cardiac disease
- Atrial fibrillation
- Dyslipidemia
- Diabetes mellitus
- Carotid stenosis
- Prior TIA or stroke
- Elevated homocysteine
- Atherosclerosis of aorta
Sacco RL, et al. Stroke 1997281507-1517. Panciol
i AM, et al. JAMA 19982791288-1292.
23Prevalence of Stroke by Age and Sex
NHANES III 1988-94
p16
Source CDC/NCHS.
24??????????????????????????????????????
1. ????????????? (Atherosclerosis)
???????????????????????????????? ???????
?????????????? ???????????????????????????
????????????????????? ?????????????????
??????????????????????????, ??????????,
?????????????????? ???? ?????????
25??????????????????????????????????????
26?????????????????????????????
27??????????????????????????????????????
2. ???????? ??????????????????????????????????????
? ??????????????????? ?????????????????????
??????????????????????? 3. ???????????????????
4. ??????????????? 5. ??????????????????????
28????????????????????????????
1. ?????????????????? 2. ????????????????????????
?????
29???????????????????
30????????????????????????
- ?????????????????????!!
- ?????????????????????????
- ??????????
- ?????????? ?????????????
- ????? ???? ??????????????
- ????????? ????????
- ???????? ???????
- ??? ????????????
31????????????????????????
1669
32????????????????????????????????????????????? ?
?????????????????????????????????
33????????????????????.
- 15-20 ?????????
- 20-30 ?????????????????????
- 50 ??????????????????????????????????
34???????????????????????????????
1. ??????? ??????????? 2. ?????????????????????
?????????????? ????? CBC, Cholesterol, ??????
... ???????????????(EKG) ?????????????? ???
??? Echocardiogram 3. ???????? ?????????
35???????????????????????????????
??????????? ?????????
1. ???????????????????? (CT scan) 2.
????????????????????????? (MRI, MRA) 3.
???????????????????????????????(Ultrasound) 4.
????????????????????????????????
36????????????????????????
37Brain CT scan in Stroke !
Abnormal
Normal
Hypodense
Hyperdense
Ischemic stroke
Hemorrhagic stroke
38Stroke Fast Track
Consider Thrombolytic Treatment
Onset 3hr CT neg Inclusion Exclusion
39???????????????????????????
1. ???????????????? ????????????????
thrombolysis Aspirin / ??????????????????????????
?
2. ?????????????? ???????? stroke
unit ???????????? ???????????? ???????????? ??
??????????????????????? ???????????????????????
(220/120 mmHg) 3.????????????????????????????????
???
40???????????????????????????
1. ??????????????????????????? ????????????? ???
??????
2. ?????????????????????????????????? ???????????
?? Angiogram ?????????
41????????????????????????
- ?????????????????????? ???? ????????? ????????
- ???????????????????? ??????????? ???????????????
- ???????????????????????????????????
42???????????????
- 1. ????????????????????
- ??????????????????????????
- ???????????????
- ????????????????????????
- ??????????????????????????????
- 2. ????????????????????????????????????
- 3. ??????????????????? ????????
43(No Transcript)
44(No Transcript)
45(No Transcript)
46(No Transcript)
47(No Transcript)
48- ?????????????????????
- ???
- ????
- ??????????????????????? Ischemic, Hemorrhagic,
Unknown - ???????????? DM, HT, DLP, Heart disease,
Smoking - ????????????
49??????????????
- ??????????????????????????????????????????????????
???.????????????????.?. 2553-?????? ?.?. 2556
??????????????? 384 ??
50?????????????????????????????????????????????????
51??????????????????????????????????????????????????
?
52(No Transcript)
53?????????????????????????????????????????????????
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54??????????????????????????????????????????????????
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55?????????????????????????????????????????????????
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56??????????????????????????????????????????????????
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57?????????????????????????????????????????????????
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58??????????????????????????????????????????????????
?
59?????????????????
- ??????????????????????????????????????????????????
??????????????? 58 ?????????????????
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60?????????????????
- ??????????????????????????????????????????????????
???96?????????25?????????????????
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61???????????????????
- ???????HosXp ???????????????????????????????.?.
2553 - ??????????????????????????????????????????????
???? ??????? meningitis, brain tumor, Bells
palsy ??????? - ??????????????????????????????????
- ????????????????????????????????????
?????????????????? ??????????????? - ?????????????????????