Research on computational biomechanics

1
Research on computational biomechanics
Qinghua Qin Department of Engineering
2
OUTLINE

1. Analytical solutions for piezoelectric bone
   remodelling
2. Tissue mechanics with FEA
3. Understanding Human Joint Mechanics Through
   Advanced Computational Models
4. Finite element 3D moving contact analysis
5. Injury biomechanics
6. Multi-field properties of biomaterials by FEA

3
2002-2006 ARC Discovery-Project, on
Thermo-electro-chemo- mechanical properties of
biological systems (AU686,825, Grant No.
DP0209487) 2004-2006 ARC Discovery-Project,
on Rheological and electrical properties of
biological soft tissues (AU249,000, with Dr Z
Liu and Dr. Y Yu, DP0451097) 2006-2008 ARC
Discovery-Project, on Theoretical and
experimental studies on magnetoelectroelastic
bone remodelling process (AU260,000, with Dr S
Kalyanasundaram, DP0665941)
4
1. Analytical solutions for piezoelectric bone
remodelling
5
(No Transcript)
6
e is a change in the volume fraction of bone
matrix material from its reference value
7
(No Transcript)
8
2. Tissue mechanics. Our research on tissue
mechanics focuses on the use of the finite
element method to examine the mechanics of soft
and hard tissues. Study how the microstructure of
material can affect material performance and how
the external electric and mechanical loading can
change their material microstructure. In
particular, study how the multi-fields, i.e.,
thermal, electrical, chemical, magnetic, and
mechanical fields can simultaneously affect the
medical performance of biological structures, and
how to use them to achieve active control in
injury healing process.
Computational Modeling of Knee Mechanics
9
3. Understanding Human Joint Mechanics Through
Advanced Computational Models development of
automated and adaptive three-dimensional (3-D)
finite element analysis and parallel solution
strategies to describe nonlinear moving contact
problems characteristic of the biomechanics of
joints in the human musculoskeletal system.
10

• 4. Finite element 3D moving contact analysis of
  biphasic problems utilizing nonlinear
  hyperelastic finite deformation laws for tissue
  and non-Newtonian laws for the fluids
• 5. Injury biomechanics, we will study mechanisms
  which may cause injury, study how we can use
  external mechanical loading, electric loading, or
  magnetic wave to help injury healing process.
  Study how damaging electric and mechanical
  loading can affect bone remodeling process,
  affect soft tissue in human body, causing injury.
  We are particularly interested in bone injury and
  injury of musculoskeletal system from movement
  and in workplace or sports.

11
6. Multi-field properties of biomaterials by
FEA The existence of piezoelectricity in bone
makes it worthwhile to try if application of
electric stimuli or magnetic stimuli can enhance
the formation of bone or soft tissue, muscle. It
is found some bone exhibits small but definite
piezoelectric property. How the electric stimuli
can affect bone growth and bone recovery. How we
can use this mechanism in medical healing
process. ApproachThe focus is to develop a
finite element model of bone remodeling process.
The constitutive law including piezoelectric
effect needs to be incorporated in the
well-established finite element software system
(ABAQUS) and validated with existing analytical
solutions. The state-of-art of the FE software
systems used in this project are based in
Department of Engineering(HYPERWORKS) and
supercomputing facility at ANU(ABAQUS) and the
student will be provided access to both the
systems.
12
Materials Research Group 1. Polymer Science
microstructure, amorphous feature 2. Smart
materials and composites A smart structure is a
structure that can sense its environment and take
corrective action when required without any
external instruction. 3. Biomaterials and
biomechanics bone remodelling, injury
biomechanics 4. Nanomaterials and nanotechnology.