NSF-NSEC for Integrated Nanopatterning and Detection Technologies

1
NSF-NSEC for Integrated Nanopatterning and
Detection Technologies (NSEC Grant Number EEC
0647560) Chad Mirkin (PI), Michael Bedzyk,
Vinayak Dravid, Horacio Espinosa, Franz Geiger,
Mark Hersam, Joseph Hupp, SonBinh Nguyen, Monica
Olvera de la Cruz, George Schatz, Richard Van
Duyne, William Klein, Chang Liu, Milan Mrksich,
Steve Sligar, Teri Odom, Steve Wolinsky, Laurie
Zoloth, Mercouri Kanatzidis, Jiaxing Huang, C.
Shad Thaxton Northwestern University, University
of Chicago, University of Illinois at
Urbana-Champaign
Education and Outreach
SRG 1 Nanopatterning
Research Experience for Undergraduates
Research Experience for Teachers

• Partnership with the Museum of Science and
  Industry, Chicago
• Resulting in 2,400 square ft permanent exhibit on
  nanotechnology
• Opening 2011
• Potential to reach over 2 million visitors per
  year
• DiscoverNano Website (www.discovernano.northwester
  n.edu)
• gt900,000 visitors a year
• Includes
• Introduction to nanotechnology
• Historical timeline
• Nano Art gallery
• Curriculum projects
• Meet the Researchers section
• Nanotechnology Town Hall Meetings
• Introduces nanotechnology to the public
• Addresses societal/ethical concerns
• 7 meetings held, 600 attendees to date
• Nanoscience Pre-college Module
• Inquiry-based, links to real-world applications,
  extensively field-tested
• Includes student teacher manuals

• 208 REU participants to date
• 50 of participants women and underrepresented
  minorities
• Hands-on research plus professional development
  activities
• Technical writing course
• Public Speaking workshop
• Tour of Argonne National Laboratory
• Final symposium and written paper
• Over 90 published papers

• Program includes hands-on research and curriculum
  development for their classrooms
• 81 pre-college teachers have participated to-date
• 9000 pre-college students impacted to-date

Dip-Pen Nanolithography Feedback
Controlled Lithography
Heteromolecular 10 million Pen Array
Intermolecular spacing with atomic precision
Nanostructures
Knowledge Transfer (to-date)

• 726 publications
• 193 provisional patents
• 1,444 domestic and international seminars
  colloquia
• 97 Frontiers in Nanotechnology Seminars
• 7 International Institute for Nanotechnology
  Symposiums
• 16 start-up companies launched through Small
  Business Evaluation Entrepreneurs (SBEE)
  Program (gt500M in VC invested)
• 20 companies enlisted in Nanotechnology Corporate
  Partners (NCP) program
• 70 Industrial partnerships
• 47 International partnerships

Nanoscape The Journal of Undergraduate Research
in Nanoscience

• 93 articles published to date
• Undergraduate authors from institutions across
  the country
• Volume VIII to be released Summer 2011
• On-line and print version
• Print version mailed to gt1,000 college and
  university departments and libraries

Polymer Pen Lithography 2-D Active
Probe Arrays Parallel Inking Wells
SRG 3Integrated Biodetection Chip
SRG 2 Signal Transduction Receptor Design
MOSFET-embedded microcantilever development
Surface immobilized bio-barcode assay
Improved bio-barcode assay
Flow
250 nm
Aperture
Lamp
Spectrometer
Flow cell
Protein biomarker identification
Detection Strategies Enabled by NanoMaterials
New Receptor Chemistries
Profiling HDAC Activity
Drug Binding to Membrane Proteins
Measuring Telomerase Activity
Integration of novel receptors with
nanomechanical detection platform