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???? (Respiratory Failure)

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Title: ???? (Respiratory Failure)

1
????(Respiratory Failure)

??????????
? ?

2
Content

??
??
??
?????????
???????????
???????

3
??????????
O2
O2
O2
1
??
CO2
CO2
CO2
(??)???
(??)????
(??)???
4
??

???????????(?)????????????????????????????,??????(
PaO2?60 mmHg)?/???????(PaCO2?50 mmHg)
,?????????????????????????
?????????
??????????

5
?????????

???????????????????????????????????????????
??????( PaO2)?60mmHg
?/?????????(PaCO2)?50mmHg

6
??
7
??

???????
?? ?? ??????
?????
?? ????? ??? ??????? ??? ARDS
?????
????? ????
??????
???? ?? ???? ?? ?????
??????
???? ?? ??? ????? ????? ????? ????????????

8
? ?

?????????
???? ???CO2??
???? ???CO2??
???????
???? ???????????????????
???? ??????????????????
???????
????????
???????
???
???

9
?????????

??????????????
?????
????
??/??(V/Q)????
???-????????
?????

?????(Hypoventilation)
(1)???????
(Restrictive ventilatory disorders)
?????????????????

(2)???????(Obstructive ventilatory disorders)
??????????????????
11
(No Transcript)
12
(No Transcript)
13
2. ????(Diffusion abnormality)?O2?CO2????????????
???????????

?????????
?????????? ??????
???????? ?????? ????????? ???? Hb?? V/Q???

14
????????????
??????
O2???? CO2????
???????
PaO2 ?PaCO2??
O2??? CO2???
PaO2 ? PaCO2 ?
PaO2 ? PaCO2 ?
???????
O2??? CO2???
15
3. ??????????? (Ventilation-perfusion-
mismatching) ?????????? ???????(VA,4L/min)?????(Q,
5L/min)???(VA/ Q)??0.8?
.

VA Q
VA/ Q ??? 1.2L/min 0.4L/min
3.0 ??? 1.8L/min 2.0L/min 0.9 ???
2.1L/min 3.4L/min
0.6 ?????????????? ?????PaO2?PAO2??????
16
(No Transcript)
17
(1) ??/??????????? (Type cause of
ventilation-perfusion-mismatching)
????????(Decreased ratio of VA/ Q)
18
(No Transcript)
19

???-????????(Increased of anatomical shunt )

?????????????????????????????????????????????
20
5. ????? ?????????????????
?? ?? ?? ????
?????
?? ??
????250ml/min, ??500ml/min, ????????????????
21
(No Transcript)
22
????????????????

??????
????
????
????
???
????
???????

23
1.??????(Alteration of nervous system)
(1)?????CNS???
24
(3)????(Pulmonary encephalopathy)
?????(Cerebrovascular injury)
PaCO2????? ????? ????? ??
?????? ????? ??? ?????
?????

?????
????
????
25
(No Transcript)
26
?????( Injurious changes)
PaO2lt 40 mmHg,PaCO2gt 80 mmHg ?????(-)
?????CO2?? ???????????(-)
???????????????????
????? ?????
?????? ??
?????
27
(2)???????????? ??????????,???????????,????????
? PaO2??CO2?? H??EDCF?EDRF????
??????K???? ?????? ???????

?????????,????
28
3. ??????(Alteration of respiratory system)
29
(2)?????????????????
?????
????
30
4.?????? ?????????RBC?? ????????? ??????? ?????
5.????? ?????? ?? ????(??? ?? ???) ??
?? ???? ??? 6.??????? ?? ????? ??
???????? ?? ???????? ??????
??DIC ?????????????
31
7. ????????????