Plaque vulnerability Key role of macrophages - PowerPoint PPT Presentation

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Plaque vulnerability Key role of macrophages

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Title: PowerPoint Presentation Author: Dee McLean Last modified by: catapano Created Date: 1/7/2003 4:42:50 PM Document presentation format: Presentazione su schermo – PowerPoint PPT presentation

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Title: Plaque vulnerability Key role of macrophages


1
Plaque vulnerabilityKey role of macrophages
2
Vulnerable plaqueKey role of the macrophage in
vascular wall inflammation
3
Fibrinogen is an independent risk factorfor
atherosclerosis
4
Vulnerable plaqueKey role of the macrophage in
the degradation of the fibrous cap
5
Thrombus formationThe macrophages release
coagulation factors
6
Tissue factorthe initiator of coagulation and
thrombogenesis in vivo
7
Oxidized LDL and thrombogenesis
8
Plaque disruption (plaque cracking, fissuring,
rupture thrombosis start point)
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