Title: EMBASE?BA?????
1EMBASE?BA?????
- ????????WinSPIRS??
- ??Excerpta Medica Database (EMBASE)
- ????EMBSE??????
- ??Biological Abstracts(BA)
- ??BIOSIS Previews ?????
2??
- ??EMBASE????????????
- ??????????????
- ??EMTREE????
- ??BA?Authority File???.
- ???????(TS)???????
- ??BA,MEDLINE?EM
3WinSPIRS??????
- ?????(WinSPIRS 5.00)
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- Database
- Print
- Download
- Searches
- Index
- Thesaurus
6(No Transcript)
7??????
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- Search?Suggest
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- Show?Retype? Limits?Clear
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- Next Hit?Previous Hit
- Brief Fields?Add to Search
- ????????
8????
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9???????
- Comput
- computer,computor,computing
- Wom?n
- woman,women
10And Or Not
- AND
- gastric and stasis ??
- Retrieves records that contain both gastric"
and stasis." - OR
- hepatitis B or hepatitis C
- Retrieves records that contain hepatitis C"
or hepatitis D" - NOT
- dyspepsia not aged ????
- Retrieves records that contain dyspepsia" ,
not concluding records that contain aged"
11And Near With
- AND
- saccharin and synthesis ??
- Retrieves records that contain both
"saccharin" and "synthesis." in the same record. - WITH
- family with stress
- Retrieves records that contain both "family"
and "stress" in the same field. - NEAR
- blastula near embryo ??
- Retrieves records that contain both
"blastula" and "embryo" in the same sentence.
12???????
- Search ??
- ????
- Suggest??
- Limit??
- ??????(??????????)
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- Index ??
- Change ???????
- Thesaurus??
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- ???? (???)
13The Power of EMBASE MEDLINE Combined!
14About EMBASE
- This bibliographic database features highly
relevant information, much of which simply cannot
be found elsewhere. Renowned for its
comprehensive international coverage, EMBASE now
contains more than 9 million records from 1974 to
the present from over 4,000 journals
approximately 450,000 records are added annually.
Over 80 of recent records contain full author
abstracts.
15EMBASE ??
- Excerpta Medica Database
- ???,?????????
- ???110?????4000???
- 1974??????????
- ????445000?
- ?????80???????
16(No Transcript)
17Features Coverage
- Drug Research, Pharmacology, Pharmaceutics,
Pharmacy, Side Effects and Interactions,
Toxicology - Human Medicine (Clinical and Experimental)
- Basic Biomedical Sciences
- Biotechnology, Biomedical Engineering and
Instrumentation - Health Policy and Management, Pharmacoeconomics
- Public, Occupational and Environmental Health,
Pollution - Substance Dependence and Abuse
- Psychiatry
- Forensic Medicine
- Alternatives to Animal Testing
18????
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19Unique benefits
- Drug literature record access through chemical
name, drug trade name or manufacturer name - Enhanced biotechnology, pharmacy and medical
devices coverage - Medical device trade name and manufacturer names
fields - Precise and reliable indexing using EMTREE, a
hierarchically-ordered, synonym-controlled
thesauruswith more than 45,000 drug and medical
indexing terms and 190,000 synonyms
(incorporating all MeSH terms)
20EMBASE ??
- 1900?????IM??
- ?24.8 ?13.2 ?11.8 ??15?(0.26)
- 40??????????,1/3??????????
- ??????,????????
- ???????DR\EL\MN\RN\TN
21EMBASE ??
- ????????,???????????????????
- ?????????,?????????
- ?????????????,??????(????MESH???)
22EMBASE CD-ROM
- Elsevier Science???1989?
- ??
- EMBASE CD
- EMBASE Drugs Pharmacology CD
- CANCER-CD
- EMBASE Specialties Series
- http//www.elsevier.nl/homepage/sah/spd/site/locat
e_embase.html
23(No Transcript)
24EMBASE CD
- Description
- Over 6 million abstracts and citations from 1980
to the present- over 4,000 biomedical journals
are screened from 70 countries. Monthly updates
will add approximately 34,000 new records. - Important drug information not covered in other
major biomedical databases - EMTREE Thesaurus incorporating a user-friendly
combination of EMTREE descriptors and medical
MeSH terms
25EMBASE????
- EMTREE
- 1988?????
- EMCLAS
- 1974-1988? EMBASE?????,
- EMTAGS
- ?????????,1998???
26EM CLASSIFICATION SYSTEM
- EC(EMCLAS)
- EMBASE?????????,?????????????,?????EC???????????
- ??EC
- ??EC??(37)1990???,???????EL??????11????
27EM CLASSIFICATION SYSTEM
- EMCLAS - Section Numbers and Headings
- 1 Anatomy, anthropology, embryology and
histology2 Physiology3 Endocrinology - 37 Drug EMCLAS 3738 Adverse reactions
titles39 Pharmacy - 52 Toxicology151 Mycobacterial diseases
(1984-1988) - ??????EMBASE????
28EM CLASSIFICATION SYSTEM
- EMTREE
- ????
- ????
- ???? (15?? 115?? ???? ???????)
- Anatomical concepts (facet A)
- Physical diseases, disorders and
- abnormalities (facet C)
- Chemicals and drugs (facet D)
- ????(????,????)(????)
29EMTREE
- 45,000??????
- 10,000???
- 190,000?????????????????NLM?MeSH???
30EMTREE
- EMTREE
-
- Stomach bleeding
- Stomach hemorrhage(???)
31EMTREE
- EMTREE????,??????? Major Medical Descriptors
(DEM), Minor Medical Descriptors (DER), Major
Drug Descriptors (DRM), and Minor Drug
Descriptors (DRR)??(2000???)?
32EMTREE
- EMTREE????
- ?????e.g. acute granulocytic leukemia
(????????? not leukemia, acute granulocytic)????
??e.g. stomach tumor (not gastric
tumors)??????????? - e.g. fetus (not foetus) ?????? e.g.
nuclear magnetic resonance (nmr is a synonym)
??????e.g. alpha adrenergic receptor
???,????,???,??,??????? - e.g. down syndrome 4 ethyl 2,5
dimethoxyamphetamine (??????)????????????????
e.g. acute lymphocytic leukemia (as well as the
broader term "leukemia")
33EMTREE
- EMTREE???
- ?????,????
- ?????????
- ???????
- ??term information?????
34EMTREE
- ??
- Hay fever(???)
- respiratory tract allergy
- allergic pneumonitis
- allergic rhinitis
- asthma
- hay fever
- house dust allergy
- nose allergy
- pollen allergy
35EMTREE
- EMTREE????
- EMTREE???????????????????????????????,??,????
????,?????,????,????,????,????????MESH???
propranolol(DOCITON?INDERAL) - paracetamol (???)
- acetaminophen and 4 acetamidophenol
- ????DRM?DRR???????????????????,?????TN??
36EMTREE
- EMTREE - Disease Link and Drug Link Terms
- Disease link terms and drug link terms are
controlled terms frequently used with a medical
or drug index term to indicate precise
associations. They have been used in EMBASE since
1988. Search for these associations by using a
hyphen between the index term and the link term
or as independent terms. For example, the search
cardiovascular-surgery in su retrieves records
that are about surgical aspects of
cardiovascular.
37EMTREE
- Disease Link Terms
-
- ComplicationCongenital disorderDiagnosisDis
ease ManagementDrug resistance (began 1996)Drug
therapyEtiology
- 14??????
-
- Epidemiology
- PreventionRadiotherapyRehabilitationSide
effectSurgeryTherapy
38EMTREE
- Disease Link Terms
- ??
- Parkinson's diseasesurgery
- 1988??
- parkinson disease and surgery(98)
- ??
- Parkinson- disease/surgery(62)
39EMTREE
- Drug Link Terms
- 17???????
-
- Adverse drug reaction
- Clinical trialDrug administrationDrug
analysisDrug combinationDrug comparisonDrug
concentrationDrug developmentDrug doseDrug
interaction - Drug therapy
-
- Drug toxicityEndogenous compoundPharmaceutic
sPharmacoeconomicsPharmacokineticsPharmacology
- 47????????
- Buccal drug administrationEpidural drug
administrationInhalational drug administration
40EMTREE
- ??
- 1.losartan (as descriptor)
545 - 2.losartan (link) drug combination 40
- 3 .losartan(link)drug comparison
125
41????
- TI - TITLE Somatic mutation theory of
carcinogenesis Why it should be - dropped and replaced
- AU - AUTHOR(S) Sonnenschein-C Soto-AM
- AD - ADDRESS OF AUTHOR C. Sonnenschein, Dept.
of Anatomy and - Cell. Biology, Tufts University
School of Medicine, Boston, MA 02111, - United States
- SO - SOURCE (BIBLIOGRAPHIC CITATION)
MOL-CARCINOG. Molecular- - Carcinogenesis. 2000 29/4
(205-211) - CO - CODEN MOCAE
- IS - ISBN/ISSN (INTERNATIONAL STANDARD
NUMBERS) 0899-1987 - PY - PUBLICATION YEAR 2000
- CP - COUNTRY OF PUBLICATION United States
- LA - LANGUAGE OF ARTICLE ENGLISH
- LS - LANGUAGE OF SUMMARY ENGLISH
- AB - ABSTRACT The somatic mutation theory of
carcinogenesis has been the dominant force
driving cancer research during the 20th century.
In brief, it
42????
- DEM - MAJOR MEDICAL DESCRIPTORS
somatic-mutation carcinogenesis- - DER - MINOR MEDICAL DESCRIPTORS
cancer-research gene-mutation
cell-proliferation metazoon- cell-interaction
stroma- neoplasm- tumor-cell human-
nonhuman- article- priority-journal - DRR - MINOR DRUG DESCRIPTORS carcinogen-
- EC - EMCLAS CLASSIFICATION Cancer- (16)
Human-genetics (22) - PT - PUBLICATION TYPE Journal
- DT - DOCUMENT TYPE Article
- RF - NUMBER OF REFERENCES 49
- AN - ACCESSION NUMBER 2001024129
- UD - UPDATE CODE 20010201
43EMBASE??????
- AB Abstract
- AD Address of Author
- AN Accession Number
- AU Author(s)
- BT Book Title
- CD Conference Details
- CF Conference Name
- CO CODEN
- CP Country of Publication
- CT Conference Proceedings Title
- DE Medical Descriptors(99???)(dem,der)
- DM Device Manufacturers Names
- DN Device Trade Names
- DT Document Type
- DR Drug Descriptors(99???)(drm,drr)
44EMBASE??????
- EC EMCLAS Classification
- ED Editor(s)
- EL EMCLAS Drug Classification
- EML E-Mail Address
- IS ISBN/ISSN (International Standard
Numbers) - LA Language of Article
- LS Language of Summary
- MN Manufacturer Names
- MS Molecular Sequence
- PB Book Publisher
- PI Publisher Item Identifier
45EMBASE??????
- PT Publication Type
- PY Publication Year
- RF Number of References
- RN CAS Registry Number
- RP Report Number
- SO Source (Bibliographic Citation)
- SU Subjects
- TI Title
- TN Trade Names
- TO Original (Non-English) Title
- TS Titles
- UD Update
46EMBASE??????
- ??
- diabetes-mellitus in DEM
- kidney-failure in der
- penicillin-derivative in drm
- ????????
- diabetes mellitus in dem ?
- diabetes- mellitus in dem??????
47EMBASE????
- EMBASE Accession Number (AN)CODEN
(CO)Country of Publication (CP)EMCLAS
Classification (EC)EMCLAS Drug Classification
(EL)ISBN/ISSN (International Standard Numbers)
(IS)Language of Article (LA)Language(s) of
Summary (LS)Publication Type (PT)Publication
Year (PY)Number of References (RF)Update
(UD)
48EMBASE????
- ??
- french in la or lafrench
- pylt1991
- orthopedic in ec ????? ec33
ud19980125-19980401
49EMBASE????
- ???????????????
- 1) hypertension
- 2) and herbal medicine
- 3) and review in dt
50EMBASE????
- ??????????????????
- 1) urinary tract infection
- 2) and child
- 3) and epidemiology in su
51EMBASE????
- ?????????????????
- brain or cranial or cerebral
- near hemorrhag
- not leukemia
52???????
- EM Printed Products
- ???(???????)
- 1946???,42???
- ????-??-??
- On-line
- DataStar,DIALOG,DIMDI,LEXIS/NEXIS,OVID,STN,Scienc
eDirect??????? - EMBASE.com
- ????
53Biological Abstracts(BA)??
54About BA
- ??????350,000?,????
- ?1980?????????????
- ???100????
- ???5200??????
- ??www.biosis.org
- www.biobis.com
55(No Transcript)
56(No Transcript)
57????????
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??,????? (14)
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?? (1)
????? (52)
58Sample Article Record
- TI Title Successful ribavirin therapy for severe
adenovirus hemorrhagic cystitis after allogeneic
marrow transplant from close HLA donors rather
than distant donors. - AU Author, Editor, Inventor Miyamura-K a
Hamaguchi-M Taji-H Kanie-T Kohno-A
Tanimoto-M Saito-H Kojima-S Matsuyama-T
Kitaori-K Nagafuji-K Sato-T Kodera-Y - AD Author Address a First Department of
Internal Medicine, Nagoya University School of
Medicine, Tsurumai-cho 65, Showa-ku, Nagoya,
466-8550, Japan - SO Source Bone-Marrow-Transplantation. March,
2000 25 (5) 545-548.. - PY Publication Year 2000
- DT Document Type Article
- IS ISSN (International Standard Serial Number)
0268-3369 - LA Language English
- LS Language of Summary English
- AB Abstract Intravenous ribavirin was given to
nine patients who had developed severe
adenovirus-induced hemorrhagic cystitis (AD-HC)
which was resistant to conventional therapy or
where there was involvement of other organs after
allogeneic BMT. Three patients recovered
completely from AD-HC, two of whom had been
resistant to vidarabine. All three had received
sibling BMTs (2 HLA matched, 1 HLA
mismatched).. - AI Abstract Indicator Y
59Sample Article Record
- MC Major Concepts Infection- Hematology-
(Human-Medicine, Medical-Sciences) Pharmacology- - ST Super Taxa Adenoviridae- Animal-Viruses,
Viruses-, Microorganisms- Hominidae- Primates-,
Mammalia-,Vertebrata-, Chordata-, Animalia- - OR Organisms adenovirus- (Adenoviridae-)
pathogen human- (Hominidae-) patient, adult - TN Taxa Notes Animal-Viruses Animals-
Chordates- Humans- Mammals- Microorganisms-
Primates- Vertebrates- Viruses- - CB Chemicals and Biochemicals HLA- ribavirin-
antiviral-drug - DS Diseases adenovirus-induced
hemorrhagic-cystitis AD-HC urologic-disease,
viral-disease - RN CAS Registry Number (R) 36791-04-5 RIBAVIRIN
- MQ Methods and Equipment allogeneic-marrow-transp
lantation therapeutic-method - MI Miscellaneous Descriptors clinical symptoms
- AN Accession Number 200000129172
- UD Update Code 20000425
60??????
- Biological Abstracts ????????????
- ???????,??????
- ?????(Free text)
- ??(Truncation)
- ??(Abbreviations)
61????(Authority File or Thesaurus)
- ??????,????????
- ???????????
- ?BIOSIS?????? www.biosis.org/authorityfile.html
62(No Transcript)
63????Thesaurus Branches
- Chemicals Biochemicals (cb)
- Drug modifiers
- Sequence Data (sd)
- Sequence type modifiers
- Geopolitical Location(ge)
- Institutions and Organizations (nc)
- Institution type modifiers
- Major Concepts(mc)
- Organism(or)
- New Taxon modifiers
- Fossil modifiers
- Super Taxa(st)
- Taxa Notes(tn)
- Diseases(ds)
- Disease modifiers
- Parts, Structures, Systems (ps)
- Organ System modifiers
64??????
- TERM DETAIL FOR Pharmacology
- SCOPE NOTE The development or use of
- drugs for the diagnosis, prevention, or treatment
of - disease in animals and humans includes drug
- design, testing and clinical trials, drug
- pharmacokinetics, and pharmacodynamics
- studies.
- Tree 1 of 1 Major Concepts
- Major Concept Terms
- Pharmacology Pharmaceuticals Pharmacognosy
65???????TS
- ????
- MC (major concepts )
- ST (super taxa)
- MQ (methods equipment)
- CB (chemicals biochemicals)
- MI (miscellaneous Descriptors )
- NC (institutions organizations)
- RN (CAS registry numbers )
- DS (diseases)
- OR (organism names )
- GE (geopolitical location)
- SD (sequence data)
- IN ( industry)
- PS ( parts, structures systems)
- YN ( taxa notes)
- TM (time)
- NP ( persons)
66??????
- ??????????
- Turkey 759 (no field limit)
- Turkey in TS 692 (Title Subject
Terms) - Turkey in GE 399 (Geopolitical
Location) - Turkey in OR 245 (Organism)
67??????Major Concepts
- ?????????????????????
- ??Authority File?????????
- ???? hematology in MC medical sciences in
MC pharmacology in MC - ???? Infection- Hematology- (Human-Medicine,
Medical-Sciences) Pharmacology-
68??????Parts, Structures Systems
- ?????????????? (e.g. organ systems, body parts)
- ?????? (Authority File) organ system modifiers
- ???? digestive-system in PS
- ???? cerebellum- nervous-system
liver-tissue digestive-system, postmortem-
69??????Diseases
- ????,??,????,??????
- ?????? (Authority File) controlled disease
modifiers - ???MeSH?????Alternate Indexing field???
- ????
- viral-disease in DS hemorrhagic cystitis in
DS ?????? - ???? adenovirus-induced-hemorrhagic-cystitis
AD-HC urologic-disease, viral-disease
70??????Alternate Indexing
- MeSH?????
- ???? arthritis rheumatoid in ALT??????
- ????Alternate Indexing Arthritis,-Rheumatoid
-(MeSH)Diseases Rheumatoid-arthritis
connective- tissue-disease, immune-system-diseas
e
71??????Alternate Indexing MeSH Examples
- BIOSIS Diseases field
- prostate-cancer neoplastic-disease,
reproductive-system-disease/male - cancer neoplastic-disease leukemia
blood-and-lymphatic disease, neoplastic-disease
- Alternate Indexing
- Prostatic-neoplasms- (MeSH)
- Leukemia-(MeSH) Neoplasms-(MeSH)
72??????Chemicals Biochemicals
- ????????????????
- ?????(Authority File) ?,????Drug modifiers
- ???? ribavirin in CB ???
- hla in CB
- ???? HLA- ribavirin- antiviral-drug
73??????CAS Registry Numbers
- CAS Registry Numbers???????,??????????
- ????
- 36791-04-5 in RN
- ????
- 36791-04-5 RIBAVIRIN
74??????Methods and Equipment
- ????????????????????
- ???????
- ???? ???
- allogeneic marrow transplantation in
MQ therapeutic method in MQ - ???? allogeneic-marrow-transplantation
- therapeutic-method
75??????Sequence Data
- Sequence Data ???????????????????
- ?????? (Authority File) ??????
- ???? AF001177 in SD
- ???? AF001177- GenBank-, amino-acid-sequence
U89896- GenBank-, amino-acid-sequence, - nucleotide-sequence
76??????Time (Geologic)
- ???????,?????????????
- ???? Paleozoic in TM ???
- ???? Cambrian- Paleozoic- Devonian-
Ordovician- Paleozoic- Silurian- 21st
century 18th century
77??????Geopolitical Location
- ?????????????????
- ??????(Authority File)??????
- ????
- Austria in GE
- USA in TS
- ???? USA- (North-America, Nearctic-Region) Aust
ria- (Europe-, Palearctic-Region)
78??????Person
- ??????????????
- ???? Charles Darwin in NP Albert Einstein in
NP - ???? Charles Darwin biologist Albert
Einstein inventor
79??????Industry
- ?????????????
- ???? biotechnology industry in
IN pharmaceutical industry in IN - ???? pharmaceutical industry biotechnology
industry
80??????Institutions Organizations
- ??????????????????????
- ???????????Controlled Institution Type Modifiers
- ???? Monsanto in NC
- ???? Monsanto Company, company/organization
81??????Miscellaneous Descriptors
- ?????????????????????
- ???? clinical symptoms in MI
- ???? clinical-symptoms immune-system-activation
Meeting-Abstract
82????????
- ???????? Super Taxa Taxa Notes Biosystematic
Codes - ????? Organisms Title Descriptors
Controlled Vocabulary(Thesaurus)
83?????????Super Taxa
- ????????????????????????
- ??????(Authority File)???????
- ???? viruses in ST hominidae in ST
- ???? Adenoviridae- Animal-Viruses, Viruses-,
Microorganisms- Hominidae- Primates-,
Mammalia-, Vertebrata-, Chordata-, Animalia-
84?????????Taxa Notes
- ????????????
- ?????? (Authority File) ????????
- ???? nonhuman mammals in TN humans in TN
- ???? Animal-Viruses Animals- Chordates-
Humans- Mammals- Microorganisms-
Nonhuman-mammals Primates- Vertebrates-
Viruses-
85?????????Organisms
- ????????????,????????????
- ???? human in OR (bottlenose dolphin OR
tursiops truncatus) in OR adenovirus in OR
??? - ???? Adenovirus- (Adenoviridae-) pathogen-
human- (Hominidae-) adult-, patient-bottlenose-d
olphin
86????????Organisms
- ???????????????,????????,??,????,???
- ????NEAR???????
- ???? (human NEAR patient) in OR (acarina NEAR
new-species) in OR (rat NEAR animal model) in OR - ???? Adenovirus- (Adenoviridae-) pathogen-
human- (Hominidae-) adult-, patient- rat-
(Muridae-) animal-model Equus-caballus
horse- (Equidae-)
87??????????
- ?????????????
- ???? (Authority File) ???????????????
- ????(Authority File)??????????????
88????????
- human in OR humans in TN Hominidae in OR
includes fossil species - ????????,???,?????
- ???? (human NEAR female) in OR
- ???? human- (Hominidae-) female-, patient-,
child-
89?????????
- ?????? (Authority File) ???????
- ??????????????????
- ????????????
- ?????
90??1
- ????????????????????
- ?????(animal model AND alzheimer) in TS
- ?????animal model in OR AND Alzheimer in DS
91??2
- ????????????????????
- ?????
- ((IBUPROFEN OR MOTRIN) AND
- ANTIPYRETIC AND ANALGESIC) IN TS
- ?????(IBUPROFEN OR MOTRIN) NEAR (ANTIPYRETIC AND
ANALGESIC) IN CB15687-27-1 in RN AND
(antipyretic and analgesic) in CB
92?? 3
- ????????????????
- ????(population studies AND (megaptera
novaeangliae or humpback whale) AND north
pacific) in TS - ?????population studies in MC AND (megaptera
novaeangliae or humpback whale) in OR AND north
pacific in GE
93????
- ???Publication year py2000 pygt1998 py1998-199
9 - ????Document Type
- ????Languages
- ????Summary Languages
- ????Abstract Indicator
- ??Update
94Updates
- Quarterly updates on CD
- Update code????????????
- ???? UD20001128
95BIOSIS Previews
- ???????????????????????????????????
- ????????Biological Abstracts?Biological
Abstracts/RRM?BioResearch Index? - ??100????????5500?????1650???????????,???28?????
96BIOSIS/MEDLINE/EMBASE Serials
BIOSIS vs MEDLINE
BIOSIS vs EMBASE
97BIOSIS/MEDLINE/EMBASEPrimary Emphasis
MEDLINE Biomedicine Clinical Medicine
Experimental Medicine Nursing Dentistry Public
Health Genetics Toxicology Pharmacology Allied
Health Sciences
EMBASE Drug Research Pharmacology Human
Medicine Basic Biological Research Health Policy
Management Public, Occupational and
Environmental Health Substance Dependence
Abuse Psychiatry Forensic Science Biomedical
Engineering Instrumentation
BIOSIS Life science areas Agriculture Biochemistr
y Biomedicine Biotechnology Botany Ecology Environ
mental Sciences Genetics Microbiology Pharmacology
98BIOSIS/MEDLINE/EMBASE Value added indexing
BIOSIS Relational Indexing Controlled natural
language keywords Broad subject Broad organism
group Supertaxa
EMBASE Hierarchical tree Drug indexing Trade
names Manufacturer names Routes of
administration Clinical Trials
MEDLINE Hierarchical medical tree Topical
subheadings Check tags
99??!
- ?????????? ??
- ??65122062
- binzhang_at_library.imicams.ac.cn