Title: THE EFFICACY AND SAFETY OF
1THE EFFICACY AND SAFETY OF SHORT PULSE
ERBIUMYAG LASER IN THE TREATMENT OF ACQUIRED
MELANOCYTIC NEVI
Mete Baba, Deniz Seçkin, Nebil Bal Baskent
University Faculty of Medicine Department of
Dermatology and Pathology
2No study evaluating the efficacy and safety of an
erbiumYAG laser with its small penetration depth
and fewer adverse effects in the treatment of
acquired melanocytic nevi.
3To investigate the efficacy and safety of short
pulse erbiumYAG laser in the treatment of
acquired melanocytic nevi
4Patient selection and consent Laser
treatment Follow-up Biopsy and histopathologic
assessment
5Benign-appearing melanocytic nevi (clinically and
dermatoscopically) Nonfacial localization Diame
ter lt 6 mm Flat or just palpable
62940 nm
1 J
5 Hz
300 µs
7Wound healing Infection Scarring Pigmentary
changes
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914 patients (10 women and 4 men aged, 21-38
years mean, 32.6 years). Four to ten pulses of
laser irradiation were sufficient for clinical
removal of all nevi Epithelization time was
between 7 and 10 days Redness persisted up to 3
weeks in all cases
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12Epidermis normal Dermis mild fibrosis ranging
between 0.19-0.28 mm (mean, 0.24
mm) Perivascular lymphocyte and eosinophil
infiltration 7 specimens Several melanophages
4 specimens
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14The depth of vaporization 2-4 µm for each 1
J/cm2, 4 to 10 pulses of erbiumYAG laser
irradiation at fluencies between 5.2 and 14.4
J/cm2 are sufficient to remove nevus cells in the
dermo-epidermal junction and the upper dermis.
In 1 nevus in this study, incomplete
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16Laser ? Malignant transformation
17 Erbium YAG lazer safe and effective