Oregon Clinical and Translational Research Institute

1
Oregon Clinical and Translational Research
Institute

• Funding Focus What OCTRI can do for you

Shawn W. Radcliffe, MSFront Door Program
ManagerBridget Adams, MSHS, CCRAResearch
Support and Services
2
What can OCTRI do for you?

• How does OCTRI support research during the
  funding phase?
• Research services to support your project
• Kaiser Permanente Northwest (KPNW)
• OCTRI funding opportunities
• OCTRI Scholars - support for new investigators
• Costs and fee structure
• Finding more information

3
How does OCTRI support research during the
funding phase?

• There are many ways in which OCTRI can help you
  when you are submitting an application for
  funding
• Investigator Support and Integration Services
• Front Door your gateway to OCTRI
• Biostatistics and Design Program
• Community Research and Engagement
• Translating Research Into Practice Policy

4
Investigator Support Integration Services

• Pre-study regulatory submission services
• Protocol development
• IRB, Radiation Safety, and Biosafety applications
• Grant application services
• Budget development
• Data and Safety Monitoring Plan (DSMP)
  development
• Regulatory support services
• Regulatory Consultation

5
OCTRI Front Door

• Single point of contact to access OCTRI programs.
• Knowledgeable staff at OHSU and KPNW
• Provides information about OCTRI
• OCTRI Programs
• Research services
• Funding opportunities
• Description of OCTRI and its programs to include
  in your funding application
• Provides letters of support and cost estimates of
  OCTRI services for funding applications
• Seeks out and develops collaborations between
  investigators

6
Biostatistics Design Program

• Grant applications and protocol development
• Sample size and power analysis
• Statistical analysis plan
• To receive biostatistics consultation including
  grant development support, investigators need to
  contact OCTRI at least four weeks in advance of
  deadlines.

7
Community Research and Engagement

• Public health research guidance
• Social and behavioral research guidance
• Population engagement consultation

8
Translating Research Into Practice Policy

• Consultation in the development of clinical
  research that has greater applicability to
  practice and policy.
• Consultation in the transfer of knowledge into
  practice and policy, including
• Practice-based research networks
• Oregon Evidence-based Practice Center
• OCHIN Practice Management

9
Research services to support your project

• Biomedical Informatics
• Database design
• Scannable forms
• Large-scale clinical trials coordination
• Translational bioinformatics (e.g. genomics)
• Clinical Translational Research Center
• Nursing services inpatient and outpatient
• Study coordinators
• Bionutrition and body composition cores
• Core laboratory
• Assays
• Genetic analyses (DNA, RNA, SNP, cell separation)
• Biostatistics
• Study implementation
• Data analysis
• Manuscript preparation
• More

10
Kaiser Permanente Northwest (KPNW)

• Some KPNW resources are available to OHSU
  investigators, including
• Patient recruitment (e.g. mailings, flyers,
  clinic visits)
• Clinical trials unit
• Electronic Medical Record (EMR)
• Human tissue biolibrary, with links to the EMR
• KPCHR collaborators
• The Front Door can answer questions about these
  resources and assess feasibility and cost

11
OCTRI Funding Opportunities

• Pilot Project Funding
• Supports the generation of preliminary data that
  will launch new NIH R proposals (or similar)
• 30,000 per award, 2 RFAs per year
• Career-Development Pilot Project Funding
• Supports the generation of preliminary data that
  will launch new NIH career-development proposals
  (or similar)
• 15,000 per award, 2 RFAs per year
• Oregon Scholars in Clinical Research (OSCR KL2)
• Oregon Students Learn Explore Research (OSLER
  TL1)

12
OCTRI Scholars - support for new investigators

• OCTRI Scholar status is granted to highly
  qualified and motivated new investigators who
  also have excellent support from their academic
  units.
• This type of support is open to
  clinical/translational investigators
• with an existing career-development award and
  preparing to apply for larger funding
• applying for first career-development award in
  (e.g. K-award)
• OCTRI supports OCTRI Scholars by providing
  research services for their primary project
• More information and an online application is
  available on the OCTRI website under Education
  Training

13
Costs and Fee Structure

• OCTRI has extensive research services available
  for all studies, regardless of funding source.
• OCTRI may be able to subsidize, partially or in
  full, the cost of some services for certain
  investigator-initiated studies, including
• Studies intended to generate preliminary data
• Partially-funded studies requiring additional
  resources
• Requests for subsidized research services are
  evaluated according to OCTRI priorities, which
  include
• Junior investigators with well-established goals
  for launching careers primarily devoted to
  clinical and translational research
• New translational research projects that are
  likely to lead to competitive national funding

14
Finding More Information

• As with all funding applications, it is best to
  plan ahead. Please contact the Front Door when
  you are preparing your application to find out
  how OCTRI can help you.
• Shawn Radcliffe (OHSU), octri_at_ohsu.edu, (503)
  418-9790
• Dan Sapp (KPNW), octri_at_kpchr.org, [phone]
• Or visit www.octri.org