Retinopathy of Prematurity (ROP)

1
Retinopathy of Prematurity (ROP)

• Melissa Andrews
• BME 281 Sec 2

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What is ROP?

• Affects the retinal blood vessels of premature
  babies
• Retina forms early in development but blood
  supply does not
• Affects 500 to 700 babies in U.S each year
• The more premature the higher the risk

• High Risk
• lt32 weeks
• lt3 pounds

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Exams

• High-risk infants should have retinal exams
• Depending on gestational age first exam usually 4
  - 9 weeks after birth
• Babies 27 weeks or later have their exam at 4
  weeks of age
• Follow-up exams

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Optical Coherence Tomography (OCT)

• Noninvasive
• Usually forms 2-D images
• 3-D pictures can be formed

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Spectral Domain Optical Coherence Tomography (SD
OCT)

• Duke University Medical Center
• Hand held
• Narrow beam of broadband light sources
• 3-D scanned image
• 40 times faster than previous OCT
• Faster less time spent to diagnosis and faster
  recognition of ROP

• Baby can remain in incubator during procedure

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Treatments

• Treatment should start within 72 hours of the eye
  exam
• Plus disease babies need immediate treatment
• Cryotherapy (freezing)
• Laser therapy
• Surgery is needed if the retina detaches

• Plus Disease

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References

• New Device To Detect Blindness In Babies
  Biomedical Engineering News." Biomedical
  Engineering Biotechnology News Events. 16
  Aug. 2010. Web. 03 Oct. 2011. lthttp//www.biomedic
  alblog.com/new-device-to-detect-blindness-in-babie
  s/22000/gt.
• Retinopathy of Prematurity MedlinePlus Medical
  Encyclopedia." National Library of Medicine -
  National Institutes of Health. 4 May 2011. Web.
  03 Oct. 2011. lthttp//www.nlm.nih.gov/medlineplus/
  ency/article/001618.htmgt
• Pediatric Ophthalmology Video
  (Ophthobook.com)." The Free Online
  Ophthalmology Book! (Ophthobook.com). Web. 03
  Oct. 2011. lthttp//www.ophthobook.com/videos/pedia
  tric-ophthalmology-videogt.
• Retinopathy of Prematurity - Symptoms, Diagnosis,
  Treatment of Retinopathy of Prematurity - NY
  Times Health Information." Health News - The New
  York Times. Web. 03 Oct. 2011. lthttp//health.nyti
  mes.com/health/guides/disease/retinopathy-of-prema
  turity/overview.htmlgt.
• Huang, D., E. Swanson, C. Lin, J. Schuman, W.
  Stinson, W. Chang, M. Hee, T. Flotte, K. Gregory,
  C. Puliafito, and Al. Et. "Optical Coherence
  Tomography." Science254.5035 (1991) 1178-181.
  Print.
• "Retinopathy of Prematurity." Wikipedia, the Free
  Encyclopedia. Web. 5 Oct. 2011.
  lthttp//en.wikipedia.org/wiki/Retinopathy_of_prema
  turitygt.
• "ROP Retinopathy of Prematurity Treatment." Get
  EyeSmart - Eye Health Information for the Public
  from the American Academy of Ophthalmology. Web.
  6 Oct. 2011. lthttp//www.geteyesmart.org/eyesmart/
  diseases/retinopathy-prematurity-treatment.cfmgt.
• All Pictures are from Google imagines for the
  purpose of education in this presentation