Spectral Domain Optical Coherence Tomography (SD-OCT)

1
Spectral Domain Optical Coherence Tomography
(SD-OCT)

• Analicia Behnke
• November 27, 2012

2
SD-OCT

• SD OCT screens for retinopathy of prematurity in
  babies eyes
• Uses narrow beams of light to penetrate deep
  layers of tissue and produce a 3-D image of
  posterior section of an infants eye

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What is retinopathy of prematurity?

• Eye disorder effecting premature infants
• Weighing less than 2.75 pounds
• Born earlier than 31 weeks
• ROP is caused by abnormal growth of blood vessels
  in the retina, causing the retina to be pulled
  out of position and even become detached
• Five stages, ranging from mild abnormal growth to
  detached cornea

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Cause of ROP

• Abnormal growth happens because normal retinal
  development doesnt complete until a few weeks
  after birth
• Before blood vessels reach edge of retina, growth
  stops.
• The edge of the retina doesnt receive enough
  oxygen so it sends out signals to other areas of
  the retina for nourishment, resulting in abnormal
  growth of vessels.
• New blood vessels are fragile and can break
  easily causing bleeding and scaring, which pulls
  on the retina when they shrink, causing a
  detached retina

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Testing for ROP

• Usually tested about 4-6 weeks after birth
• Eyelid speculum is used to keep the eyes open
• Lens with a light will be used to look in the
  babies eyes
• Use a scleral depressor to move the eye into
  different positions

• OCT- Optical Coherence Tomography
• Reflects light to create 2D and 3D images of the
  eye
• Used moving reference mirror to measure the time
  it took for light to be reflected
• Lengthy process
• Limited image quality

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SD-OCT

• Developed at Duke University
• Measures multiple wavelengths of reflected light
• 100 times faster
• 40,000 pictures per second for clearer images
• TruTack technology- Tracks eye movement during
  imaging
• Detect changes during the scan

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Benefits

• Hand-held probe allows the baby to stay in the
  incubator during testing
• Allows for cross-sectional images of the retina,
  allowing for better visualization
• Reduces time spent on diagnosis
• Faster diagnosis, faster treatment, less damage
  to an infants vision

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Sources

• "New Device To Detect Blindness In Babies
  Biomedical Engineering Biotechnology News." New
  Device To Detect Blindness In Babies Biomedical
  Engineering Biotechnology News. N.p., 16 Aug.
  2012. Web. 17 Nov. 2012. lthttp//www.biomedicalblo
  g.com/new-device-to-detect-blindness-in-babies/220
  00/gt.
• Facts About Retinopathy of Prematurity (ROP)."
  Facts About Retinopathy of Prematurity NEI.
  N.p., n.d. Web. 24 Nov. 2012. lthttp//www.nei.nih.
  gov/health/rop/rop.aspgt.
• "Eye Exam for Retinopathy of Prematurity by
  Alexandra Howson, PhD." Eye Exam for Retinopathy
  of Prematurity. Beth Israel Deaconess Medical
  Center, 2008. Web. 25 Nov. 2012.
  lthttp//www.bidmc.org/YourHealth/MedicalProcedures
  .aspx?ChunkID588196gt.
• "Spectral-Domain Optical Coherence Tomography
  (SD-OCT)." Heidelbergengineeringcom RSS.
  Heidelberg Engineering, 2012. Web. 25 Nov. 2012.
  lthttp//www.heidelbergengineering.com/us/products/
  spectralis-models/technology/spectral-domain-oct/gt
  .
• Lee AC, Maldonado RS, Sarin N, O'Connell RV,
  Wallace DK, Freedman SF, Cotten M, Toth CA.
  "National Center for Biotechnology Information."
  (2011) n. pag. Print.