Title: Tissues and Organs Comprising the Immune Response System
1Tissues and OrgansComprising the ImmuneResponse
System
Where components of the immune
response originate, differentiate, meet,
interact, and function
Folder Title TissOrg
2APC and T-Cells
3Marcophage and T-Cell Kissing
4Macrophage to T-Cell Interaction
5Helper T-cell B-Cell Interaction
CD4 co-receptor
6B-Cell Activation
See figure 2-7, Kuby, 4th Ed., p. 36
7B-Cell Small, Blast, and Plasma
See Figure 2-7, Kuby 4th Ed. p. 36
8Where do these cells originate? Where do they go
to interact with each other? Where do they carry
out their functions?
9Primary and Secondary Lymphoid
Related to Figure 2-13, Kuby, 4th Edition, p. 47
10(No Transcript)
11Animations Produced for Kuby Immunology Online
Link http//bcs.whfreeman.com/immunology6e/ (In
Class Do animations from the Book CD) Chapter 2
Animation. Cells and Organs
12Exactly what kind of Cell is the one attached to
the B-Cell? (exactly means not just its
general type of cell, but specifically what type
of cell it is based on what this figure shows
that the cell is doing)
Rank Responses
1
2
3
4
5
6 Other
13Thymus Photo
14Thymus Cartoon
Diagrammatic Cross Section of Thymus. Figure
2-14, Kuby, 4th
Edition, p. 48
ThymusCross
15CD4 and CD8 in Thymus
16MALT and M-Cells
See Figure 2-22, Kuby 4th Ed. p. 56
17(No Transcript)
18(No Transcript)
19MALT and IgA
See Figure 2-22 Kuby, 4th Ed. p. 56
20CD Antigen Table
CDMarks
21CD Antigens Color Coded
22Animations Produced for Kuby Immunology http//bc
s.whfreeman.com/immunology6e/ Chapter 11
Animation. Signal Transduction
23CD Antigen List Pages A1 to A26 339
Entries, 2007 Edition of Kuby
How to Understand CD Antigens 5 Persons in a
Room Person 1 5 ft 5, 160 lbs bespectacled
old geezer Person 2 5 ft 11, 280 lbs, 22-year
old guy, all muscle Person 3 5 ft 5, 135
lbs, 20-year-old woman Person 4 7 ft 1 , 200
lbs, 22 year-old guy Person 5 5 ft 8, 150
lbs, 22 year-old guy
24This is a fill-in-the-blank question. Please
enter your responses as a series of numbers from
1 to 5. Which PersonA. Is a varsity
basketball player?B. Plays on the womens
field-hockey team?C. Is a boring old
professor?D. Is a varsity football player for
SU?E. Is a cross-country runner?__ __ __ __
__
Person 1 5 ft 5, 160 lbs bespectacled old
geezer Person 2 5 ft 11, 280 lbs, 22-year old
guy, all muscle Person 3 5 ft 5, 135 lbs,
20-year-old woman Person 4 7 ft 1 , 200 lbs,
22 year-old guy Person 5 5 ft 8, 150 lbs, 22
year-old guy
25Secrets of Signaling 1. How Do You Knock on a
Door? 2. Why does the phone ring more than
once? 3. Why can the police officer directing
traffic blow his whistle only once? 4. Why does
your computer say Are You Sure You Want to
Delete File XYZ? 5. When the class was directed
to do Bunny Ears behind the person next to
them, only a few persons responded. Why was
that? 6. A different set of persons responded
when asked to raise their right hand. Why was
that?
26Secrets of Signaling (2) 7. Only the guys in the
front of the room responded when I invited the
class to do what all classes would love to do to
a pain-in-the next Prof. Why was that? 8. I
asked the class to raise both hands but no one
complied. Why is that?
27Signal, Receptors, and co-receptor Pairs
28Costimulatory signals B7 CD28
29Costimulatory Signals T-Cell to MPh
30Cancer Eluding Costimulatory Signal
31CDs on B, T, and NK Cells
32T-Cell ALL Markers
(ALL Acute Lymphocytic Leukemia)
Kuby, 5th Edition p. 157
33Pre-B-Cell ALL Markers
(ALL Acute Lymphocytic Leukemia)
Kuby, 5th Edition p. 157
34B-Cell CLL Markers
(CLL Chronic Lymphocytic Leukemia)
Kuby, 5th Edition p. 157
35Leukocyte Recirculation
36Lymphocyte Recirculation
37(No Transcript)
38Leucocytes in Capillaries Cartoon
39Leucocytes in Capillaries Photo
40Extravasation of Naïve T-Cell into Lymph Node
41Adhesion Leucocytes to Endothelium
42(No Transcript)
43(Non-inflamed Endothelium)
44CAM Cell Adhesion Molecules
45Membrane of CirculatingLeucocytes
General Structures of Cell Adhesion
Molecules (CAMs) Kuby, 3rd Edition
Figure 15-2a
CAMStruct
Endothelial Cells Lining Capillaries
46(Inflamed Endothelium)
47CAMinCap Adhesion in Capilaries
48Animations Produced for Kuby Immunology
OnLine Link http//bcs.whfreeman.com/immunology6
e/ In Class Use Book CD Chapter 2 Cells of
the Immune-system (Static) Cell Death
(Animated) Chapter 11 Signal Transduction
(Animated) Chapter 4 Immunoglobulins
(Static) Chapter 13 Animation. Leukocyte
Extravasation (Animated)
49Please put away all notes and any devices except
for your Turning Point NXT Transmitter. No
papers or computers on your desk please. No
communication between or among students.
50(No Transcript)
51Animations Produced for Kuby Immunology http//bc
s.whfreeman.com/immunology6e/ Or search Kuby
Immunology, Click on Kuby Immunology 6e , go
to Student Resources Chapter 2 Cells Cell
Death (Also chapter 10) Chapter 11 Signal
Transduction Chapter 13 Leucocyte Extravasation
52Actin Cytoskeleton Linkage to Collagen
Extra-cellular Matrix
Figure 19-14 ECB 1998, p. 603
Collagen
Fibronectin
Integrin
Plasma Membrane
Actin Microfilament
MFtoECM
53CAMFamly
Tissue-target Cells in Red
Leucocyte CAM in Blue
On Leucocytes
On Endothelial Cells
On Endothelial Cells
On Neutrophils
On Mucosal Epithelium
On Leucocytes
On Endothelial Cells
Families of Cell Adhesion Molecules Kuby, 3rd
Ed. Figure 15-2b
CamFamly