Title: ??????(invasive mole)??????????????????,????????????????????????,????????,?????????,??????????
1???????????
2??
- ??????(invasive mole)??????????????????,?????????
???????????????,????????,?????????,?????????? - ????(choriocarcinoma)?????????????????????????????
??????,???????????????????
3??
- ?????????????????????????????????,?????????,??????
???????????????????????????,??????????????????????
???????????????,????????????
4- ???????????,??????????,???????????,??????,????????
,?????,???,???,??????????????????????????,??????,?
?????????????,????????????????????
5(No Transcript)
6????
- 1.??????????????????????????
- (1)??????????????????,???????????,?????,?????????
?????????,?????????? - (2)?????????????????????46???????????,?????
7- (3)?????????????????HCG?????,???????????????
- (4)???????,??????????????????????????????????????
???????? - (5)???????????,???????,????????,??????????,??????
??
8- 2.?????????????,?????????????????????????,???????
?,??????????,?????????????? - (1)?????????????????????????????????????,????X???
?CT????? - (2)??????????????,??????,????????????,??????
- (3)???????????????????????????????
9(No Transcript)
10- (4)???????,??????????????????3?,??????,??????????
?????????????????????????,????????????????????????
?????,????????? - (5)????????????????????????????
11(No Transcript)
12??
- 1.???? ????????????????????????,????????????????
??????????????????
- ?ß-HCG??
- B?????????????????????????????????
- X????????????
- CT????????????????????
13(No Transcript)
14- 2.????????????????????????????????,?????????????
?????????????,???????,??????
15????
??? ??? ???? ????? ???? ?? ??? ????? ?? ??
???? ? ??? ???? ???? ???? ?? ??? ??? ? ??6??? ???12?? ??1?? ? ? ?? ? ? ? ? ? ?,?? ??? ??? ??? ?,?? ???? ??,??? ? ??? ??? ???? ??? ?? ?? ?? ??? ??? ???? ? ? ? ? ? ? ?? ? ? ? ? ? ? ??? ? ? ?? ? ? ? ?? HCG ? ?
16?????????
?? ??????? ?? ????,?????????(?????????) ?? ??????,????????? ?? ??????
17?? 0 1 2 4
?? lt40 40 - - ???? ??? ?? ??? - ??????? lt4 4 lt7 7 lt 13 13 ???? HCG lt lt lt ??????(cm) - 3lt5 5 - ???? ? ??? ?? ??? ?????? - 14 58 gt ?????? - - ?? ?????? ?????
18??
- ?????,???????????????,???????FIGO????????,????????
????,??????????? - 1.????????????(MTX),? ??D,5-FU,CTX,VCR??
- I?????????,II-III???????,IV?????????????
19(1)??????
?? ??,????,?? ????
MTX 0.4mg/(kg.d)????,??5? 2? Act-D(?KSM) 8-10ug /(kg.d)????,??8-10? 2? 5-FU 28-30mg /(kg.d)????,??8-10? 2? VP-16 200mg/(m2.d)??,??5? 2? MTX 1mg /(kg.d)????,?1,3,5,7? 2? CF 0.1mg/(kg.d)????,?2,4,6,8? (24????)
20(2)????
?? ??,????,???? ????
5-FUKSM 5-FU 26-28mg/(kg.d),????8? 3? KSM 6ug/(kg.d),????8? ACM Act-D 400ug???? ?1,4,7,10,13? 4? CTX 400mg???? ?2,5,8,11,14? MTX 20mg???? ?3,6,9,12,15?
21EMA-CO??
???? EMA ?1? VP16 100mg/m2 ???? Act-D 0.5mg ???? MTX 100mg/m2 ???? MTX 200mg/m2 ????12?? ?2? VP16 100mg/m2 ???? Act-D 0.5mg ???? ?????(CF)15mg,???? (?????MTX????24???,?12? ?1?,?2?) ?3? ?????15mg,????,?12??1?, ?2? ?4??7? ??(???) ???? CO ?8? VCR 1.0mg/m2,???? MTX 600mg/m2,????
22(3)????
- ????????,???????B-HCG,????,B?,??,CT??????????18??,
?B-HCG?????????????
23(4)??????
- ???????,????????,?????,???????????????????,???,?,?
??????????????,????????,?????
24(5)????
- ????????????????,????????,HCG??????,??3???,???2-3?
?????????5?????????
252.??
- (1)?????????,????????????????????????????????,???
????????????????????HCG???????????????????????????
??????????,??????????? - (2)????????????????????
26- 3.??????????,??????????????????
- 4.?????????????????????????,??,??,?????????????PV
B(??,????,????),BEP(????,????,??) - VIP(????,?????,?????)??????????????????
27??
- ??????????,????????1?,????3??????3?,????1??5??????
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