Silly Yak Disease

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Silly Yak Disease

• Ariana Berlin

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Celiac Disease

• Other names
• Celiac sprue
• Gluten-sensitive enteropathy
• Nontropical sprue
• Coeliac sprue
• Endemic sprue
• Gluten intolerance

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Mode of Inheritance

• This is a genetic disease
• It is located on the short arm of the sixth
  chromosome
• It is autosomal recessive
• Approximately one out of every 133 people have
  celiac. However, only 3 of these people have
  been diagnosed

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Punnett Square

• Because this disease shows incomplete penetrance,
  somebody who has celiac may not have the allele
  and somebody who has the allele may not have the
  disease.

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Symptoms of the Disorder and Detection

• Stomach cramping and bloating
• Increasing appetite
• Back pain
• Constipation
• Dehydration
• Diarrhea

• Energy loss
• Fatigue
• Muscle
• cramping
• Dry skin
• Weight loss
• Depression

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Detection

• There is no way to detect the disease before
  symptoms appear
• It is impossible to know if somebody is a carrier
  because of incomplete penetrance

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Diagnostic Testing

• First, they have a physical examination, which
  includes a series of blood tests. Second, a
  duodenal biopsy is performed with many samples
  from multiple locations in the small intestine.
  Third, the gluten-free diet is started. When the
  symptoms subside and the small intestine returns
  to its normal, healthy state, then the diagnosis
  of Celiac is confirmed.

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Prognosis

• Celiac is not necessarily life threatening unless
  a gluten-free diet is not started and the stomach
  does not stops being able to work properly
• The only known treatment is a gluten free diet

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Current Research

• Scientists are currently researching many new
  treatments
• A specially bred wheat species that is minimally
  immunogenic
• Some other treatments that are being studies deal
  with killing the bowel lining cells

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Genetic Counseling

• A genetic counselor can not usually predict that
  a child will have celiac. If they find out that a
  child does, however, they can explain the diet
  and how to live by it.

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Graphics
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Additional Interesting Facts

• The Celiac Foundation has Team Gluten Walks. For
  more information on these walks go to
  www.celiac.org
• May is national Celiac Awareness Month
• Some shampoos contain gluten in them, so a person
  with celiac has to be careful when buying
  shampoo.
• Passover is often very difficult for people with
  celiac because matzo contains gluten and so does
  most other kosher for Passover foods. They often
  buy oat matzo.

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Credits

• http//www.csaceliacs.org/CD.php
• http//www.celiac.org/cd-main.php
• http//en.wikipedia.org/wiki/CeliacTreatment
• http//digestive.niddk.nih.gov/ddiseases/pubs/celi
  ac/index.htm