Title: Ribosomes
1Ribosomes
Mol. Biol. of the Cell
2Prokaryotic ribosome
Mol. Biol. of the Gene
3Eukaroytic ribosome
Mol. Biol. of the Gene
4Sedimentation of ribosomes
Mol. Biol. of the Gene
5The ribosome cycle
Mol. Biol. of the Gene
6Polyribosomes (polysome)
Mol. Biol. of the Gene
7Peptidyl transferase reaction
Mol. Biol. of the Gene
8tRNA binding sites
Mol. Biol. of the Gene
9Overview on translation initiation
Mol. Biol. of the Gene
10Ribosome binding site (Shine-Dalgarno sequence)
on mRNA
Mol. Biol. of the Gene
11Internal start site are important for
polycistronic mRNAs
Mol. Biol. of the Cell
12N-formyl methionine
Mol. Biol. of the Gene
13Initiation factors bound to the ribosome
Mol. Biol. of the Gene
14Sequence of events during initiation in
prokaryotes
Mol. Biol. of the Gene
15Capping
Mol. Biol. of the Gene
16Translation initiation in eukaryotes
Mol. Biol. of the Gene
17Start codon identification in eukaryotes
Kozak sequence at start codon G/ANNAUGG
Mol. Biol. of the Gene
18Circular polysomes in eukaryotes
Mol. Biol. of the Gene
19Circular polysomes
Mol. Biol. of the Cell
20Short upstream ORFs in eukaryotes
Mol. Biol. of the Gene
21Internal ribosome entry sites in eukaryotes (IRES)
Mol. Biol. of the Gene
22Overview of the elongation phase
Mol. Biol. of the Gene
23Binding of aa-tRNA to the A-site
EF-Tu protection of ester from hydrolysis check
for correct codon recognition
Mol. Biol. of the Gene
24Codon recognition by the anticodon
Mol. Biol. of the Gene
25EF-Tu GTP hydrolysis in codon recognition
Mol. Biol. of the Gene
26Accommodation as the second recognition control
step
Mol. Biol. of the Gene
27Translocation
Mol. Biol. of the Gene
28Release factors
Class I (stop codon recognition) prokaryotic RF1
UAG, UAA RF2 UGA, UAA eukaryotic eRF1 UAA,
UAG, UGA Class II (diss. of class I
factors) RF3 eRF3
Mol. Biol. of the Gene
29Action of release factors
Mol. Biol. of the Gene
30Ribosome recycling factor
Mol. Biol. of the Gene