HOSTMICROBE RELATIONSHIPS AND DISEASE PROCESSES

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HOSTMICROBE RELATIONSHIPS AND DISEASE PROCESSES

• CHAPTER 14

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Symbioses

• Mutualism
• Commensalism

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Symbioses

• Parasitism
• Opportunism

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Infection and Disease

• Contamination
• Infection
• Disease

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Pathogenicity Concepts

• Pathogenicity
• Virulence/Avirulence

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Normal Microflora

• Populations
• Resident
• Transient

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Kochs Postulates

• 1. specific causative agent must be observed
• 2. The agent must be isolated and grown in pure
  culture.
• 3. Hosts must get the same disease when
  inoculated.
• 4. The agent must be reisolated and show to be
  the same causative agent.

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Satisfying Kochs Postulates
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Kinds of Disease

• Infectious/Non-infectious
• Communicable/Non-communicable

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How Microbes Cause Disease

• Direct Action
• Bacterial Toxins
• Cytopathic Effects

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Virulence Factors
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Vocabulary Terms

• Sign
• Symptom
• Syndrome
• Sequelae

• Acute
• Chronic
• Subacute
• Latent

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Vocabulary Terms (2)

• Local infection
• Focal infection
• Systemic infection

• Septicemia
• Bacteremia
• Viremia

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Vocabulary Terms (3)

• Primary infection
• Secondary infection
• Superinfection
• Mixed infection

• Inapparent (subclinical) infection

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Infectious Disease Stages

• Incubation
• Prodromal
• Invasive

• Decline
• Convalescence

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Disease Stages and Microbe Populations
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Control of Infectious Disease

• Drugs
• Immunization
• Sanitization
• Future Challenges