Diagnosis made

1
Diagnosis made
Antenatal
Postnatal
Consent
Consent
Cleft team inform national cleft centre and Crane
Cleft team inform national cleft centre and Crane
Cord blood taken
yes
no
DNA / Cell line
Blood taken by phlebotomy at time of primary
closure
Blood taken from parents by phlebotomy at
outpatient clinic
Blood taken from parents by phlebotomy at
outpatient clinic
yes
no
yes
no
DNA / Cell line
no
yes
Saliva buccal cell DNA collection
Saliva buccal cell DNA collection
DNA / Cell line
Blood taken from child by phlebotomy at
outpatient clinic
DNA / Cell line
yes
no
Saliva buccal cell DNA collection
DNA / Cell line
Blue DNA from child, Red DNA from parents