Inhalants, GHB

1
Inhalants, GHB

• Examples
• Behavioral and Neural Effects
• Use and Abuse

2
Inhalants

• Solvents
• Aerosols
• Gases
• Nitrites

3
Inhalants - Uses

• Sniffing
• Spraying
• Bagging
• Huffing
• Balloons
• Dusting

4
Inhalants

• Alcohol-like Effects
• Slurred speech
• Uncoordination
• Euphoria
• Dizziness
• Light-headedness, hallucinations, delusions

5
Inhalants

• Pharmacology
• Absorption
• Bioavailability
• Receptors
• Tolerance
• Dependence

6
Inhalants

• Long-term effects
• Weight loss
• Muscle weakness
• Disorientation
• Inattentiveness
• Lack of coordination
• Irritability
• Depression

7
Inhalants

• Death!
• Sudden sniffing death
• Asphyxiation
• Suffocation
• Coma
• Convulsions/Seizures
• Choking
• Fatal injury

8
Inhalants

• Brain damage
• Basal Ganglia
• Cerebellum
• Pons
• Thalamus
• Cognitive deficits

9
Issues of Concern
Percent of 8th Graders Reporting Lifetime Use of
Inhalants Increased

Percent

P lt .05
10
GHB

• Depressant
• Therapeutic uses
• Bodybuilding

11
GHB

• Behavioral effects
• Pharmacology
• Absorption
• Reinforcement
• Possible receptor mechanisms
• GABA
• Specific receptor
• Use and Abuse