Translating Evidence into Recommendations GRADE Lunch

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Translating Evidence into Recommendations
GRADE Lunch LearnAHRQ Annual
MeetingSeptember 8, 2008

• Tess Miller, DrPH

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Be Transparent

• In how you collect synthesize the evidence
• In how you judge the evidence and make a
  recommendation

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Separate Roles

• One group collects synthesizes the evidence
• One group judges the evidence makes a
  recommendation

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Provide Clear Instruction

• Purpose of the guideline/ recommendation
• Standardize practice improve clinical outcomes
  etc.
• Framework for Reviewing the Evidence
• PICO (Patient population Intervention
  Comparison Outcomes
• Analytic Framework

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USPSTF Analytic Framework on Screening for a
Disease
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Judging the Strength of Evidence

• Guideline developers should clarify method(s)
  language for judging the strength of the evidence
• Guideline developers should consider the end
  user
• Who is it
• How will they use the guideline
• Translate the strength/quality of the evidence

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Translation Table for Assessing the Strength of a
Body of Evidence
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Consider Computer Actionability

• Develop standards to use when there is no
  evidence
• Make no statement
• Consensus approach

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Remember TransparencyThank you