College of Physicians

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Hematology Working Group
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Working Group Report

• Activity 2006-2007
• Chair, Virginia Marsh resigned and Anne Raby took
  over the responsibility of the 2007 cross Canada
  morphology survey
• We often have a teleconference in January to
  discuss the morphology survey however this year
  we organized the survey via email
• This morning we had representatives from British
  Columbia, Alberta, Saskatchewan, Manitoba,
  Ontario, Quebec, Nova Scotia and Newfoundland and
  Labrador

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Working Group Report

• Objectives for 2006-2007
• Publications
• Blood Film Morphology External Quality Assessment
  Surveys A Canadian Proficiency Testing
  Initiative
• Toward Abandoning the Band Gwen Clarke
• Standardization of Lymphoid Terminology Gaynor
  Williams
• Conduct 2007 Cross Canada Morphology Survey

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Working Group Report

• Accomplishments in 2006-2007
• Raby A, Clarke G, Crawford L, McBride E, Marsh V.
  Blood Film Morphology External Quality Assessment
  Surveys A Canadian Quality Assurance Initiative.
  
• Poster presented at Canadian Society of Medical
  Laboratory Science (CSMLS). Winnipeg, Manitoba,
  May 2006 and at the Canadian Association of
  Pathologists in Newfoundland, July 2006
• Published in Can J Med Lab Sci, 2006.
  68(5)178-187.

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Online http//www.qmpls.org/eqa/eqa_morp.html
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Working Group Report

• 2007 Cross Canada Morphology Survey, case of
  chronic myelogenous leukemia (CML)

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Working Group Report

• CLINICAL DATA PROVIDED TO PARTICIPANTS
• The patient was a 27-year-old male who presented
  in Emergency with left lower leg pain, no
  lymphadenopathy, and mild tenderness in right
  abdominal upper quadrant.
• Reference 
• Lkc 106.4 ? 109/L 4.010.0
• Erc 3.27 ? 1012/L 4.56.5
• Hb 89 g/L 135170
• Hct 0.25 L/L 0.400.51
• MCV 77.2 fL 7997
• Thrombocyte 100 ? 109/L 150400
• Main features left shift and microcytosis and/or
  hypochromasia in the morphology description.

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• Photomicrograph showing peripheral blood
  neutrophilia with left-shift, including bands,
  metamyelocytes and myelocytes

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• Plans for 2007-2008
• Submit the Band article to CMAJ
• Distribute the Lymphocyte paper to labs after
  final review
• 2008 Morphology survey
• Coagulation Questionnaire (instrumentation,
  reagents and POCT)
• Circulate Saskatchewan and Alberta RBC Morphology
  Reporting Criteria to Committee for comments

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Working Group Report

• Highlight
• -Conference call planned for January 2008
  otherwise will communicate via email