Brookhaven Lab: A Regional Science

1
Brookhaven Lab A RegionalScience Technology
Leader
Praveen Chaudhari Director Brookhaven National
Laboratory December 14, 2004
2
About Brookhaven Lab

• Founded in 1947 by Associated Universities Inc.
• Operated by Brookhaven Science Associates since
  March 1, 1998
• Battelle, Columbia, Cornell, Harvard, MIT,
  Princeton, Stony Brook, Yale
• Current staff of approximately 2,700 (600
  scientists)
• More than 4,000 facility users annually
• FY04 budget 445 million, 398 million from DOE
• NIH NASA NRC DoD DHS - 45 million

3
Brookhavens Mission

• Undertake high-risk, long lead time research in
  key DOE science technology mission areas
• Physical Sciences, Life Sciences, Technology
• Conduct accelerator, detector, and
  instrumentation research and support the nations
  science and technology enterprise
• Provide facility users with the most powerful
  tools available for scientific and technical work
• Partner with industry to ensure the U.S. lead in
  science and technology
• Provide educational opportunities for the future
  generation of U.S. scientists and the community
• Transfer innovation and technology to the market

4
Brookhaven Accomplishments

• Home to six Nobel Prizes -- five in physics and
  one in chemistry
• Development of technetium-99m, used to diagnose
  heart disease, other ailments in 11 million
  Americans each year.
• Development of L-dopa for the treatment of
  Parkinsons disease
• First chemical synthesis of human insulin
• Development of thallium-201, used in heart stress
  tests
• Development of the T7 gene expression system,
  used worldwide to produce proteins for research
  and industry
• Invention of the worlds first video game in 1958

5
Brookhavens Major Facilities
RHIC
BLIP and BAF
AGS Complex
Materials Science
Isotope Production
PET
MRI
Chemistry LEAF
Instrumentation
Tandem
Physics
Computing
National SynchrotronLight Source
Medical Research
Biology
STEM CDIC
6
Relativistic Heavy Ion Collider

• Worlds newest and biggest particle accelerator
  for nuclear physics research
• 1,042 users from 144 institutions

• Collides heavy gold ions at nearly the speed of
  light
• Evidence for quark-gluon plasma, colored glass
  condensate found, more experiments to confirm

7
Other Physics Initiatives

• Muon g-2 Testing the Standard Model
• Dark Matter/Dark Energy Large Synoptic Survey
  Telescope
• Rare Symmetry Violating Processes - Funded in
  FY05

Large Synoptic Survey Telescope
Muon g-2
Rare Symmetry Violating Processes
8
National Synchrotron Light Source

• Produces x-ray, ultraviolet, and infrared beams
  for research in physics, chemistry, medicine,
  materials science, and more
• 2,400 visiting researchers each year
• Research highlights how nerves and muscles work
  smaller, faster computer chips understanding
  arthritis/osteoporosis

9
National Synchrotron Light Source-II

• State-of-the-art, medium-energy electron storage
  ring
• Designed to deliver world-leading x-ray
  brightness, more than 10,000 times brighter than
  the current NSLS

10
Center for Functional Nanomaterials

• One of five DOE nanocenters
• Will provide researchers with state-of-the-art
  capabilities to fabricate and study materials at
  the nanoscale

• Examples Improved solar energy conversion more
  efficient catalysts new drugs stronger and
  lighter materials
• Construction begins 2005 fully operational by
  2008

11
Biology and Life Sciences

• World-renowned neuroimaging program on addiction,
  obesity, multiple sclerosis, and more
• Basic studies of DNA and proteins, microbes and
  plants, medical isotopes and cancer
• Research on the biological effects of space
  radiation and measures to protect future
  astronauts

12
Center for Translational Neuroimaging

• Features network of complementary brain-imaging
  tools (PET, MRI)
• Major medical themes include studying
  relationships between genes, the brain, and
  behavior in drug addiction, eating disorders, and
  aggression and factors that contribute to
  neurodegeneration
• Research goals include development of new
  radiotracers, imaging methods and techniques, and
  instruments, and imaging awake animals

13
NASA Space Radiation Laboratory

• Unique in simulating the harsh cosmic and solar
  radiation environment found in space
• Uses beams of heavy ions from Labs Booster
  accelerator

• Features dedicated radiobiology beamline,
  state-of-the-art specimen-preparation areas
• Hosts more than 75 users from 20 institutions
  worldwide

14
Computational Biology Center

• Working with Department of Energy to establish a
  
  Computational
  Biology Center at Brookhaven
• Regional resource for industry, universities
• High-end machines, support staff, research group
• Extensive use by NIH-funded researchers,
  industry
• New, massively parallel computers will have
  significant impacts in biology but are expensive,
  specialized, and require staff for effective
  utilization
• Why Brookhaven?
• Large concentration of users in Northeast
• Builds on experience with QCDOC
• Support from BNL core universities, Stony Brook,
  Sloan-Kettering, Cold Spring Harbor, Rockefeller
  University

15
Computational Biology Center (contd)

• Structure Prediction and Modeling Understanding
  the mechanism by which botulinum toxin penetrates
  cell membranes.
• Drug - Protein Interactions Studying anti-cancer
  agents - activators of the p53 tumor suppressor
  protein
• Computer-assisted protein engineering
  Re-engineering enzymes (desaturases) that modify
  plant oils

16
Energy, Environment, and National Security

• Developing sensors to detect and intercept
  chemical, biological, and radiological materials
• Testing fuel cells, biofuels, and other
  alternative power sources
• Exploring relationship between air quality,
  Earths climate and ecosystems

17
Fueling Local and State Economy

• FY 2003 employee salaries, wages, and fringe
  benefits accounted for 274 million, or 62
  percent, of the Labs total budget - employees
  spend locally
• 2004 economic report - Direct spending in N.Y.
  State by Brookhaven staff and users from fiscal
  1993 to 2003
• Totaled more than 4.76 billion
• Caused States output of goods and services to
  increase by 9.2 billion and created 79,000
  secondary jobs
• FY05-FY14 projected Brookhaven spending will
  increase State output 11 billion, create 91,000
  secondary jobs, strongly benefit States key
  manufacturing industries

18
Brookhavens Regional Relationships

• Brookhaven is a vital resource for scientists and
  industry in N.Y. State and the Northeastern U.S.
• More than 1,000 N.Y. State facility users SUNY
  schools IBM Albert Einstein College of
  Medicine Columbia University Corning Northrop
  Grumman, Howard Hughes Medical Institute New
  York University Pfizer Rockefeller University
• NSLS Thirty-four percent of users come from N.Y.
  institutions, making N.Y. scientists the largest
  user group. Another 22 percent come from nearby
  Northeastern states
• NSLS-SUNY connection 179 Stony Brook researchers
  using NSLS to study geology, cell biology, and
  more
• RHIC-SUNY connection More than 50 Stony Brook
  researchers studying the state of matter at the
  dawn of the universe

19
A Passion for Discovery