Role%20of%20IT%20in%20Bioinformatics

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Role of IT in Bioinformatics

• Naveena.Y

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What is bioinformatics ?

• Study of Information content and information flow
  in biological systems and processes
• Definition varies depending upon the domain of
  person who is giving the definition

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What was the reason behind the emergence of a
separate domain, bioinformatics ?
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Brief History

• Insulin 1956
• Yeast trna 1960s
• PDB 1972
• Swissprot 1986
• Human Genome
• Initiated 1988
• Completed 26th Jun 2000

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Where does the data come from?
Database 3 Ex Interpro
Composite
Database 2 Ex Swissprot
Secondary
Database 1 Ex Genbank
Primary
Publish
Wet Lab Research
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Central Dogma of Life
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What is their in each of this?

• DNA A,C,T,G
• RNA A,C,U,G
• Protein
• AUGACGAGAAGGAGUAGAAGUAG

M
V
Codon Table
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Protein Structure
Secondary
Primary
Quarternary
Teritary
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IT is used in different areas

• Functional Genomics
• Proteomics
• Drug Discovery
• Plant Biotechnology
• Molecular Modeling

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Challenges

• Protein Structure Prediction
• RNA Structure Preditction
• Drug Discovery
• Pharmacogenomics

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Questions ?
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Thank You