Pharmacology Training Programs

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Pharmacology Training Programs in the Future
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Major Accomplishments in Pharmacology and Impact
of other disciplines. (partly from ASPETs
Significant events in Pharmacology)
1978 - Discovery of G proteins -
biochemistry 1981-1983 - ANP - physiology/biochemi
stry 1988 - ANP receptor Guanylyl Cyclase -
biochem/mol. biology 1987 - Zidovudine effective
against HIV - virology/immunology Late 80s to
90s - Structures of G proteins (ras, Gi?, Gs?,
G??) biochem/structural biol 1997 -
structure of adenylyl cyclase -
biochem/structural biol 2000 - structure of
rhodopsin (GPCR) - biochem/structural biol 90s -
current - transgenics and knock outs -
genetics/mol. biol./physiol/pathology
.
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Pharmacology
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Pharmacology Students/Postdocs
Other (writing Patent law, etc)
Industry
Academia
Govt. (CDC NIH, etc.)
Administration
Science (RD)
Teaching
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• Needs on curriculum How much do we teach?
• What do we teach?
• More Biochemistry? Proteomics?
• Systems Biology/ Computational Biology
  (Mathematical
• Modeling)? - Collaborations with biology/math
  depts.
• joint programs?
• Small molecule screens? (interactions with
  industry)
• Intellectual Property and Patenting? (ditto)
• More genomics/genetics?
• Structure based inhibitors/activators? Structural
  Biology?
• Administration? Ph.D/MBA programs?

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Enhance the translational side of
research Collaborations with Clinicians
(co-mentors/committee members) - insights into
clinical trials Collaborations/Partership with
Industry (scholarships/fellowships)
Co-mentors in Industry? Advantages Learn
hands-on the processes that contribute to drug
development - analyses of clinical trial data
Gain insights into the nuances of how
Industry works - from data books, proprietary
rights, to research priorities. Make informed
decisions about careers in industry. Hurdles
Time away from primary lab Delay in
publications! Commitment on part of
industry? - investment?