Chem 375. Skim the entire chapters.

1
Chem 375. Skim the entire chapters. Focus on
the pages indicated below. Chapter 8 pp.
195-206 Problems 2, 3, 4, 8 Chapter 9 pp.
220-223, 233-end Problems 1, 8, 10 Chapter
10 pp. 239-260 Problems 4, 5, 6 Chapter 13
pp. 361-572 Problems 2-6, 8, 10 Chapter 14
pp. 382-412 Problems 2-6, 8, 9, 11
2
(No Transcript)
3
VVP p 407
4
(No Transcript)
5
Phosphoglycerate Kinase harvesting the energy of
1,3 BPG
Free energy -18.8 kJ!! Pulls GAP DH reaction
forward (free energy 6.7 kJ)
6
(No Transcript)
7
Fig 14-22 p 408 in VVP
8
Fig 14-24 p 411 in VVP
9
hexokinase
Fig 15-1 p 427 in VVP
10
(No Transcript)
11
Fig 14-13 p 399 in VVP Pyruvate kinase
12
Fig 14-14 p 400 in VVP
13
Fig 14-15 p 400 in VVP
14
Fig 14-16 p 401 in VVP
15
VVP p. 402
16
LDH
VVP p. 402
17
TPP
VVP Fig 14-18
18
H3C
?
site of pyrophosphorylation.
Thiamine (Vitamin B1)
19
Fig 14-20 p 405 in VVP
20
Fig 14-20 p 405 in VVP
21
Fig 14-20 p 405 in VVP
22
Fig 14-20 p 405 in VVP
23
Fig 14-20 p 405 in VVP
24
VVP Fig. 13-10
25
VVP p 405
26
VVP fig 14-25
27
VVP Fig 14-26
28
Fig 15-1 VVP p 427
29
Fig 15-2 VVP p 428
30
Fig 15-4 VVP p 430
31
Fig 15-4 VVP p 430
32
Fig 15-6 VVP p 433
33
Fig 15-7 VVP p 433
34
Fig 15-8 VVP p 434
35
VVP p 442
36
Fig 15-12 VVP p 441
37
Phosphorylation glycogen degradatrion
Dephosphorylation glycogen synthesis
Fig 15-20 VVP p 447
38
Fig 15-20 VVP p 447
39
(No Transcript)
40
Fig 15-1 VVP p 427
41
1) ATP synthesis equivalents NADH, FADH2 GTP 2)
metabolite clearing house
Fig 16-1 VVP p 467
42
Aerobic
Anaerobic
VVP p 484
43
(No Transcript)
44
Fig 16-2 VVP p 468
45
Fig 16-5 VVP p 472
46
Acetyl Coenzyme A (Acetyl CoA)
Figure 13-9 p 369 in VVP
47
Fig 16-2 VVP p 468
48
Fig 16-5 VVP p 472
49
VVP p 473
50
VVP p 474
51
H3C
?
site of pyrophosphorylation.
Thiamine (Vitamin B1)
52
Fig 16-6 VVP p 467
53
VVP p 474
54
Fig 17-10 VVP p 503
FAD R ribitol-P-AMP
55
Fig 16-5 VVP p 472
56
VVP p 480
H
R
R
H
2H 2e-
See Fig 17-10 VVP p 503
57
Fig 16-2 VVP p 468
58
Fig 16-9 VVP p 477
59
site of acetyl group attachment
Vitamin B3
Coenzyme A Fig 3-5 VVP p 46
60
Fig 16-9 VVP p 477
61
Reaction occurs only at this bond
VVP p 481
62
Fig 16-9 VVP p 477
63
from Acetyl-CoA
VVP p 476
64
VVP p 476
65
Fig 16-10 VVP p 477
66
VVP p 478
Mechanism see Pyruvate DH
67
Fig 16-11 VVP p 479
68
VVP p 479
69
VVP p 480
H
R
R
H
2H 2e-
See Fig 17-10 VVP p 503
70
VVP p 482
71
VVP p 482