Animal Health Meets Human Health

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Animal Health Meets Human Health

• Daryll Emery M.S., PhD., CSO
• 1801 Biotech Avenue N.E.
• Willmar, MN 56201
• DaryllE_at_Epitopix.com

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Epitopix is an outgrowth of successful
agriculture business
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Epitopix

• Privately held veterinary biologics company
• Staff of 51
• Founded in 2002
• Located in , Willmar, Minnesota

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Epitopix
Manufacturing
Research and Development

• 18,000 sq ft facility RD Facility
• 13 full time employees
• Discovery Target Antigens
• Animal Challenge models
• Proof of efficacy
• Potency

• 38,000 sq ft manufacturing facility
• 38 full time employees
• Fermentation Harvest
• Subunit/antigen purification
• Formulation/bottling
• Finished product/shipping

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Strategic Vision

• Epitopix is focused on developing novel, highly
  efficacious animal vaccines
• Technology platform based on proprietary SRP
  technology
• Strive to be a profitable, stand-alone vaccine
  company that is
• aggressively driving towards development,
  licensure and commercialization of important
  vaccine candidates in the animal health industry

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Epitopix Food Safety Strategy

• First initiative Food Safety Vaccinate
  animals to reduce the introduction of pathogens
  to the human
• food chain
• Each year in the United States Consumption of
  food contaminated with microbial pathogens causes
  an estimated
• 76 million illnesses
• 325, 000 hospitalization
• 5,000 deaths
• Salmonella
• 1.4 million cases per year Salmonella Cattle
  Vaccine licensed 2004
• 600 deaths annually
• E. coli O157
• 73,000 cases per year E. coli O157 Cattle
  Vaccine Licensed 2009
• 2000 hospitalization
• 60 deaths

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Commercialization Milestones

• Secured Intellectual Property Portfolio
• 39 U.S. Patent and Filed Applications
• USDA Licensed Products
• Salmonella Newport Approved 2004 attained 30
  market penetration in the Dairy industry within
  three years of introduction
• E. coli O157 - First USDA Approved Food Safety
  Vaccine 2009
• New Product Development
• 5 late stage USDA animal vaccine pathways

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• 1000 Westgate Drive
• St. Paul, MN 55114
• Info_at_Syntiron.com

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Syntiron

• Syntiron is a vaccine biotechnology company based
  in St. Paul, Minnesota. In 2004, Epitopix in
  conjunction with Willmar Poultry Company,
  incorporated Syntiron to adopt the Epitopix
  Siderophore Receptor and Porin (SRP) technology
  to develop human vaccines

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Syntiron

• Syntiron is developing human vaccines based on
  the SRP platform technology to combat a wide
  range of bacterial diseases, including
• Hospital Infections
• MRSA (Staphylococcus aureus)
• Pseudomonas
• Food and waterborne Infections
• Food poisoning (Salmonella, E. coli,
  Campylobacter)
• Dysentery (Shigella, Vibrio cholera and E. coli)
• Bacterial Warfare agents
• Plague (Yersinia pestis)
• Anthrax (Bacillus anthracis)
• Melioidosis (Burkholderia)

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