Georgetown University

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Georgetown University

• Chuck Wolfe
• wolfec_at_georgetown.edu

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Campus Description

• Medical Center (GUMC)
• 8 Research Buildings
• Main Campus
• 32 Campus Buildings including Dorms,Staff and
  Academic
• 6 Ancillary Buildings connected via 100Mbps

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GUMC Network

• Gigabit Core
• Building Distribution Frames (BDFs) have a Dual
  Gigabit connection to the core
• Floor Switches have a Gigabit connection to the
  BDFs
• User provided with 10/100 connection

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Main Campus Network

• OC-12 ATM core
• Server Farm has OC-12 connections to the core
• BDFs have dual OC-3 connections to the core
• Floor Switches have 100-200Mbps links to the BDFs
• User provided with 10 or 10/100 connection

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Remote Site Connections

• OC-3 ATM
• Frame-Relay
• FNS (10Mbps)
• T-1

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Internet 2

• Connected via ATM utilizing Unspecified Bit Rate
  (UBR)
• Primary connection to Abilene through MAX
• Currently being used to test teleradiology
  application in the study of ALD

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What is ALD?

• Adrenoleukodystrophy is a rare genetic disorder
  that is often fatal in young boys.
• It affects 1 in 20,000 people world-wide
• A neurological disorder that destroys the myelin
  in the brain
• Myelin insulates nerves and allows conduction of
  impulses between parts of the body
• MRI permits early detection of nervous system
  damage and is a sensitive indicator of disease
  progression

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Why are Multi-Center Clinical Trials Needed

• No institution has enough patients to perform a
  randomized control study
• ALD trained physicians are few due to the rarity
  of disease
• Sharing of film images is difficult in an
  analogue world

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Solution Digital ALD MRI Network

• Multiple sites can send data to a centralized
  database
• Consolidation of data provides sufficient patient
  pool for therapy evaluation
• ALD trained physicians have immediate remote
  access to the exams

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Project Description

• Development of DICOM network
• DICOM database resides at KKI
• Receives MRI studies from multiple institutions
  in US and world-wide
• Permits query/retrieve of studies by ALD trained
  physicians for review
• Utilizes secure technologies to ensure patient
  confidentiality and data integrity
• Works over standard Internet and NGI

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UMN ISIS KKI

• Requested data from UMN over NGI
• Upon receipt, immediately sent it to KKI over
  standard Internet
• Recorded transmission times
• Ran the test 7 times
• Results
• ISIS UMN averaged 242.5 seconds
• ISIS KKI averaged 2062.2 seconds

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Transmission Time UMN ISIS KKI(Seconds)
ISIS KKI 45 miles
UMN ISIS 1100 miles
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ISIS KKI

• Requested studies from KKI DICOM server to ISIS
• Ran the test 78 times over standard Internet
• Ran the test 83 times over NGI

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Throughput Internet vs. NGI
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Results

• Moving digital images is better than using film
  for sharing information
• Standard Internet is unpredictable for moving
  large data sets
• NGI supports real-time teleradiology
• Future enhancements of the NGI will be evaluated

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Current Projects at GU

• Wireless Testing with authentication to LDAP
• VoIP
• Multicasting
• QOS
• Gigabit Connection to the Internet

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• Thanks to Betty Levine and MaryLou Ingeholm in
  ISIS for ALD testing info