Functional Optical Imaging of Brain

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Functional Optical Imaging of Brain
BIOMEDICAL OPTICS RESEARCH
P R O G R A M O V E R V I E W
The maturing technologies of functional optical
imaging of the brain using near infrared (NIR)
are poised for broad-based deployment in
military, civilian, educational, and health care
applications. These applications range from
alertness/vigilance monitoring and mental
disorder assessment to the evaluation of
cognitive engagement. This safe, affordable,
portable, non-invasive, and non-intrusive
technology can be used in high stress, high
responsibility environments, as well as in health
care and academic settings.
Functional Optical Imaging of Breast
Recent advancements in functional optical
imaging of biological tissues using near infrared
(NIR) have reached a level where a much broader
based delivery of health care can be realized
with this novel modality. Its potential use as a
prescreening diagnostic tool for early detection
of breast cancer offers an important complement
to existing screening instruments that are too
expensive and/or immobile. In particular, this
safe, affordable, portable, and non-invasive
technology makes a much-needed diagnostic tool
available to underserved segments of the
population.
Institutional Collaborators / Primary Contacts
Dr. Banu Onaral, Drexel University (PA) Dr.
Kambiz Pourrezaei, Drexel University (PA) Dr.
Scott Bunce, MCP Hahnemann University (PA) Dr.
Britton Chance, University of Pennsylvania (PA)
Dr. Joseph Kolodzey, University of Delaware (DE)
Dr. Robi Polikar, Rowan University (NJ) Dr.
Kamelia Alavi, Technology Medicine, Inc. (PA)
Dr. Harel Rosen, St. Peters Hospital (NJ) Dr.
Warren S. Warren, Princeton University (NJ) Dr.
Arye Rosen, Sarnoff Corporation (NJ) Dr. Joseph
Elad, Quantum Leap Innovations, Inc. (DE) Dr.
Mike Contarino, NAVAIR (MD) Mr. James Buss,
Office of Naval Research (VA) Dr. Joseph H.
Ricker, Kessler Institute of Rehabilitation (NJ).
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FUNCTIONAL OPTICAL IMAGING OF BRAIN
P R O J E C T O N E P A G E R
The maturing technologies of functional optical
imaging of the brain using near infrared (NIR)
are poised for broad-based deployment in
military, civilian, educational, and health care
applications. These applications range from
alertness/vigilance monitoring and mental
disorder assessment to the evaluation of
cognitive engagement. This safe, affordable,
portable, non-invasive, and non-intrusive
technology can be used in high stress, high
responsibility environments, as well as in health
care and academic settings.

• Military Impact
• Monitoring pilots state of alertness/vigilance.
• Detection of sleep deprivation and its effect on
  soldier performance.
• Design of more effective customized training
  protocols.
• Healthcare Impact
• Monitoring brain function in neonates and
  geriatric patients.
• The possibility of a non-invasive, non-intrusive,
  and affordable brain imaging system.
• Investigation of mental disorders and monitoring
  success of treatment.
• Educational Impact
• Brain mapping during learning, memory, and
  cognitive tasks.
• Customization of instructional methodology to
  individual learning styles.
• Economic Impact
• The functional optical imaging technology
  platform will be the basis of new products for
  military, healthcare, and educational use.

Institutional Collaborators / Primary Contacts
Dr. Banu Onaral, Drexel University (PA) Dr.
Kambiz Pourrezaei, Drexel University (PA) Dr.
Britton Chance, University of Pennsylvania (PA)
Dr. Scott Bunce, MCP Hahnemann University (PA)
Dr. Joseph Kolodzey, University of Delaware (DE)
Dr. Robi Polikar, Rowan University (NJ) Dr.
Kamelia Alavi, Technology Medicine, Inc. (PA)
Dr. Harel Rosen, St. Peters Hospital (NJ) Dr.
Warren S. Warren, Princeton University (NJ) Dr.
Arye Rosen, Sarnoff Corporation (NJ) Dr. Joseph
Elad, Quantum Leap Innovations, Inc. (DE) Dr.
Mike Contarino, NAVAIR (MD) Mr. James Buss,
Office of Naval Research (VA) Dr. Joseph H.
Ricker, Kessler Institute of Rehabilitation (NJ).
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FUNCTIONAL OPTICAL IMAGING OF BREAST
P R O J E C T O N E P A G E R
Recent advancements in functional optical
imaging of biological tissues using near infrared
(NIR) have reached a level where a much broader
based delivery of health care can be realized
with this novel modality. Its potential use as a
prescreening diagnostic tool for early detection
of breast cancer offers an important complement
to existing screening instruments that are too
expensive and/or immobile. In particular, this
safe, affordable, portable, and non-invasive
technology makes a much-needed diagnostic tool
available to underserved segments of the
population.

• Economic Impact
•  Development of novel optical medical imaging
  equipment is of critical economic value to the
  nation.
• Regional Impact
• Use of a new medical imaging system will enhance
  the prestige of regional medical centers and
  development of new products, along with related
  job opportunities.
• Societal Impact
• The possibility of non-invasive and affordable
  breast imaging can have a significant impact on
  early detection of breast cancer in underserved
  populations.
• Military Impact
• A portable, non-invasive, inexpensive, robust,
  and compact medical imaging and diagnostics tool
  for use in telemedicine is of paramount
  importance for identifying hemorrhage in the
  battlefield.

Design of a portable handheld NIR Breast Cancer
Imager
Institutional Collaborators / Primary Contacts
Dr. Banu Onaral, Drexel University (PA) Dr.
Kambiz Pourrezaei, Drexel University (PA) Dr.
Britton Chance, University of Pennsylvania (PA)
Dr. Joseph Kolodzey, University of Delaware (DE)
Dr. Warren S. Warren, Princeton University (NJ)
Mr. James Buss, Office of Naval Research (VA)
Dr. Mike Contarino, NAVAIR (MD).