MMV: Medicines for Treating, Preventing

1
MMV Medicines for Treating, Preventing
Eradicating Malaria

• Penny Grewal Daumerie
• Director, Global Access, MMV

2
MMV at a Glance

• Public-Private Partnership
• Established in 1999 by WHO/TDR and the Pharma
  Industry
• Mandate Discover, develop and deliver safe,
  effective and affordable antimalarials to treat
  and protect people most at risk of malaria
• Diversified funding base
• Swiss Foundation based in Geneva

3
MMV works with partners in 33 countries

• Over 80 academic, industry and endemic country
  partners
• More than 600 scientists, clinicians, public
  health experts

6 countries 20 partners
10 countries 21 partners
3 countries 19 partners
14 countries 27 partners
4
Global Malaria Portfolio- Q3 2008MMV is the main
driver for antimalarial RD (50 projects)
Launch 2014 2012 2010
2008
Research
Translational
Development
Registration
Lead Opt
Phase II
Phase III
Preclinical
Phase I
Discovery
Coartem-D
Eurartesim
Isoquine
Ozonides
Novartis 9 projects
DHFR Thailand
IV artesunate
Artemifone
Pyramax
MK 4815
GSK 3 projects
Amodiaquine Artesunate
DHFR NITD
Tafenoquine
Pyridone 932121

Azithromycin chloroquine
Mefloquine Artesunate
Pyridones GSK
SAR97276 Choline
AQ13 Immtech
Artesunate Ferroquine
Others 6 projects
Macrolides GSK
SAR116242 Trioxanes
Fosmidomycin Azithromycin
DHODH
Others 53 projects
Arterolane PQP
Nat Product NITD
Blue AQ
Immucillins Einstein
Others 1 project
Non-MMV projects