Long-Term Transplant Outcome collaborative study

1
Long-Term Transplant Outcome collaborative study

• James Medcalf
• John Walls Renal Unit, Leicester

2
Why is this different to previous studies ?

• Greater depth of data
• Data collection will continue beyond transplant
  failure
• Prospective Patient Reported Outcome will be
  collected using measures of QoL, treatment
  satisfaction and well being.

3
The collaboration

• Five leading UK centres of renal transplantation
• Leeds (St James)
• Dr Es Will, Dr Chas Newstead
• Guys
• Dr John Scoble
• St Helier
• Dr Peter Andrews, Dr James Marsh
• Oxford (Churchill)
• Dr Paul Harden, Professor Peter Friend
• Leicester (John Walls Renal Unit)
• Dr Sue Carr, Prof John Feehally, Prof M
  Nicholson, Dr James Medcalf

4
The collaboration

• Department of Health Psychology, Royal Holloway
• Prof Clare Bradley, Dr Carolyn McMillan
• Department of Epidemiology, Leicester University
• Prof John Thompson
• Trent Institute for Health Services Research

5
Timescale and Milestones

• Now
• Multi-centre ethical approval
• Appointment of staff Nursing, statistical,
  Health Psychology
• Install data extraction routines
• 3rd Quarter 2005
• Begin retrospective data extraction
• Spring 2007
• Basic dataset for 3000 patients
• Spring 2008
• Further analysis including patient reported
• outcomes

6
Expected Outcomes

• Factors influencing cardiovascular risk
• Adverse effectors of patient and transplant
  outcome
• Impact of negative events on objective and
  patient reported outcomes

7
Other Benefits

• Feasibility of multi-centre collection
• Which items are there to collect, and which are
  useful?
• Enhancing patient care through access to clinical
  information
• Availability of information to the patient