Antigen-presenting cell (APC) phagocytizes and processes antigen - PowerPoint PPT Presentation

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Antigen-presenting cell (APC) phagocytizes and processes antigen

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1. Antigen-presenting cell (APC) phagocytizes and processes antigen. Allergen (antigen) ... Allergen (antigen) TH2 cell. APC presents antigenic determinant to TH2 cell ... – PowerPoint PPT presentation

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Title: Antigen-presenting cell (APC) phagocytizes and processes antigen


1
Allergen (antigen)
1
Antigen-presenting cell (APC) phagocytizes and
processes antigen
2
Allergen (antigen)
2
APC presents antigenic determinant to TH2 cell
TH2 cell
1
Antigen-presenting cell (APC) phagocytizes and
processes antigen
3
Allergen (antigen)
2
APC presents antigenic determinant to TH2 cell
3
IL-4 from TH2 cell stimulates B cell
TH2 cell
1
Antigen-presenting cell (APC) phagocytizes and
processes antigen
IL-4
B cell
4
Allergen (antigen)
2
APC presents antigenic determinant to TH2 cell
3
IL-4 from TH2 cell stimulates B cell
TH2 cell
1
Antigen-presenting cell (APC) phagocytizes and
processes antigen
IL-4
B cell
4
B cell becomes plasma cell, which secretes IgE
Plasma cell
IgE
5
Allergen (antigen)
2
APC presents antigenic determinant to TH2 cell
3
IL-4 from TH2 cell stimulates B cell
TH2 cell
1
Antigen-presenting cell (APC) phagocytizes and
processes antigen
IL-4
B cell
4
B cell becomes plasma cell, which secretes IgE
Plasma cell
IgE
5
IgE binds to mast cells, basophils, and
eosinophils
IgE
Eosinophil
Mast cell
Basophil
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