NonHodgkin's Lymphoma

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Non-Hodgkin's Lymphoma

• By Josh McKinney
• Dr. Mark Kittleson
• November 5, 2001

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What is Non-Hodgkin's Lymphoma?

• It is a heterogeneous group of malignant diseases
  originating in the lymph nodes and lymphoid
  tissue.4
• Non-Hodgkin's Lymphomas, like other cancers, are
  diseases of the bodys cells.6
• Non-Hodgkin's Lymphomas occur most often in lymph
  nodes in the chest, neck, abdomen, tonsils and
  the skin.4

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Facts about Non-Hodgkin's Disease

• Since the early 1970s about 53,000 new cases
  appear annually in the United States.8
• It has increased by 40 in the past ten years in
  England and Wales.4
• Malignant Lymphomas are two to three more common
  in males than that of females and occur in all
  age groups.5
• The reason for the increase is unknown, although
  it has been attributed to AIDS.9
• Burkitts Lymphoma is most common disorder in
  Uganda2

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Signs and Symptoms for Non-Hodgkin's Disease

• According to Malignant Lymphomas4
• Swelling of the lymph nodes
• Fatigue, unexplained fever, sweats
• Enlarged Tonsils and adenoids
• Unexplained weight-loss in the past six
  months

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Where Lymphomas are found

• T-Cells3
• Liver3
• Spleen7
• Large B-Cells8
• Null Cells2
• The Chromosome 82
• Pelvis Area1
• Abdomen1

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Types of tests for Non-Hodgkin's Lymphoma

• -Bone Marrow Tests2
• -Biopsy of Lymph Nodes2
• -Chest X-Rays2
• -Spleen Scan2
• -Complete Blood Test7
• -MRI of Head and Chest7
• -Bone Scan9

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Stages of Non-Hodgkin's Lymphoma

• According to Stage Explanation6
• Stage 1
• -Cancer is found in only one Lymph Node area or
  in one node of an organ.
• Stage 2
• -Cancer is found in two or more lymph nodes
  or on the same side of the diaphragm.
• Stage 3
• -Cancer is found in lymph node area or on
  both sides of the diaphragm.
• Stage 4
• -Cancer has spread to one or more organs
  outside the Lymph system.

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Prognosis

• Can be cured.1
• It is not infectious.2
• If less than 10 of skin is infected there is a
  good chance of it being completely cured.4
• If more than 10 is skin is infected or spread to
  lymph nodes or organs there is an unlikely chance
  of being cured.4

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Prognosis Cont

• Eat a balanced Diet2
• Try to eat fresh foods4
• Get plenty of Rest10
• Have annual check-up with doctor6

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Prevalence

• According to CancerBacup10
• Seventh most common cause of death from cancer 
• Average age of onset 42 years old
• The incidence of lymphomas (NHL) is increasing
  each year 
• Some of the increased incidence is from HIV
  patients.
• More common in males (8.1/100,000) in females
  5.7/100,000) 
• Great variation by country (Rural Poland
  1/100,000 non-Jews in Israel 9.1/100,000)

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Prevalence in Races8
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Treatments For NHL

• Radiation Therapy1
• Total Nodal irradiation3
• Chemotherapy4

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Possible Links to Non-Hodgkin's Disease

• According to What are the Risk Factors5
• -Industrial Chemicals
• -Electromagnetic Fields
• -Ultraviolet Radiation
• -People who received organ transplants
• -AIDS Patients

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Works Cited

• 1)Adult Non-Hodgkins LymphomaDescription
  http//webmd.lycos.com October 13, 2001
• 2)Cecil Textbook of Medicine 20th Edition
  Bennett and Saunders
• 3)2001 Conns Current Therapy WB Saunders
  Rakel and Bope
• 4)Malignant Lymphomas Professional Guide To
  Diseases Seventh Edition Springhouse
  Penn.
• 5) Risk Factors http//webmd.lycos.com
  October 13, 2001
• 6)Stage Explanation http//webmd.lycos.com
  October 13, 2001
• October 13, 2001
• 7)Textbook of Internal Medicine Third
  Edition William Kelley-Lippencott.
• 8)Understand Non-Hodgkin's Lymphomas
• http//webmd.lycos.com October 13, 2001
• 9)What are Lymphomas http//webmd.lycos.com
  October 13, 2001
• 10)What types of Treatments are Used
  www.cancerbacup.org.uk October 13, 2001