Bioluminescent method of

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Bioluminescent method of solution radiotoxicity
monitoring
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BESTTM Bioluminescence Enzyme System Technology
Fundamentals

• Immobilized supramolecular complex of enzymes
  and substrates of bacterial bioluminescent
  reaction
• Enzymes from unique collection of luminous
  bacteria (more 700 strains)
• Extensive database of bioassays

Rapid Detection System
Screen for Toxicity
Identification of toxicants
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BESTTM Designer Bioassays
Benefits
Select BioLum system sensitive to specific
analyte
Specificity Versatility
Optimize the substrate and enzyme concentrations
Sensitivity
Stability Consistency One-step detection
Immobilize components

• Takes 30-60 sec to get the results
• No sample preparation required
• No special training needed
• Ease of use

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BESTTM Designer Bioassays
Benefits
Select BioLum system sensitive to specific
analyte
Specificity Versatility
Optimize the substrate and enzyme concentrations
Sensitivity
Stability Consistency One-step detection
Immobilize components

• Takes 30-60 sec to get the results
• No sample preparation required
• No special training needed
• Ease of use

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The Opportunity
Cheaper Faster Better

• Highly adaptable proprietary, protected platform
• Broad screening 25,000 toxins
• Rapid/emergency screening adaptability
• Focused toxin-class identification systems
• Compatible with standard laboratory equipment
• Shelf-life of reagents up to several years
• Markets environmental, military, food, and
  healthcare

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Biological part of biosensorstransducer

• From bioluminometer to biosensors

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The cost-effective bioluminescence-based
biosensors forenvironmental control of natural
ecosystems and industry wastewaters, soil and air
quality
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Bioluminescent biosensors for space biotechnology

• to monitor the air, soil and water quality
  surrounding plants grown in closed environments
• to monitor the stress responses (the levels of
  NADH) in plants grown in Environmental Chambers
  and Mars green house

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Medical diagnostics

• endotoxicosis (blood plasma and serum, saliva),
  sports medicine (athletic coaching control),
  determination of enzymes activities
  (NAD-dependent dehydrogenases, proteases and
  antiproteases) in blood plasma and serum,
  platinoids, mutagenicity, antibiotic sensitivity
  etc.