Title: Style F 24 by 48
1Resilience Among Childhood Abuse Survivors with
Posttraumatic Stress Disorder Attachment Status
Moderates Depression Risk and Severity Following
Adversity Anthony Charuvastra MD, Patty Zorbas
MA, Marylene Cloitre PhD NYU Child Study Center
Nathan Kline Institute
DISCLOSURE Supported by the Leon Levy Foundation
Objective
Methods
Results
Conclusions
To evaluate whether Adult Attachment status was
predictive of comorbid depression in women with
PTSD and investigate whether attachment status
was a moderator of the depressogenic cumulative
impact of subsequent traumatic life events.
- Participating women were part of a randomized
controlled trial for the treatment of childhood
abuse related PTSD (n89). - Inclusion criteria female, a history of sexual
or physical abuse by a caretaker or person in
authority before the age of 18, literate in
English, age 18 to 65 years. - Exclusion criteria current bipolar disorder,
moderate to severe substance dependence,
psychotic symptoms, severe eating disorder, acute
suicidality requiring immediate clinical
attention. - Measures Structured Clinical Interview for
DSM-IV (SCID-IV), Clinician-Administered PTSD
Scale (CAPS), Beck Depression Inventory (BDI),
Adult Attachment Interview (AAI), Life Events
Checklist (LEC). Traumatic life events were
defined as events that were significant at the
time and continued to impact the person within
the year prior to assessment. - Statistical Analyses
- Data was analyzed using SPSS (version 15.0).
Associations between attachment status, early
environment variables, and depressive disorders
were measured using Chi-square analysis for
categorical variables and Pearson correlation
coefficients for continuous variables.
Hierarchical regression analyses examined whether
attachment status interacted with cumulative
traumatic life events to predict depression
severity.
- In this population, we propose that
- Adult attachment security moderates the risk of
chronic depression - Adult attachment security mediated the
relationship between the cumulative traumatic
life events and severity of depression. -
- Adult attachment states of mind appear to
function independently in their impact on risk of
depression, as no other abuse related variables
were associated with chronic depression. - Children with post-traumatic stress symptoms
are at the highest risk of developing chronic
depression, highlighting the need to address this
aspect of abuse related developmental
psychopathology.(Copeland et al., 2007)
Survivors of childhood abuse are at elevated risk
for subsequent adverse life events. - Clinically, interventions that influence
attachment states of mind may be important for
children and adults who have experienced abuse
from caretakers. Promoting secure attachment may
reduce risk for depressive reactions to
cumulative life traumas and the risk for chronic
and complex depressive disorders such as
dysthymia and double depression.
Attachment Associated With Chronic Depression
Background
28 of adults report being victims of childhood
physical or sexual abuse.(Anda et al., 2006)
Childhood abuse is associated with compromised
attachment in children and adults, and higher
rates of psychiatric disorders. Little is known
about the relationship between childhood abuse,
the development of attachment states of minds
into adulthood, and adult psychopathology.
Studies have shown that insecure attachment
status is related to depressive disorders. One
goal of this study was to determine whether this
relationship was maintained in the context of
PTSD. In addition, the accumulation of life
stressors is associated with increasing severity
of depressive symptoms and this relationship is
particularly strong among women with histories of
childhood abuse.(Kendler et al, 2004) We assessed
whether attachment status among women with PTSD
would mediate the relationship between
accumulating life traumas and depression.
Attachment Insecurity Predicts Depressogenic
Sensitivity to Traumatic Life Events
Attachment Status Secure R2 0.00 Insecure R2
0.44
BDI
30
25
20
References
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Anda, R. F., V. J. Felitti, et al. (2006). "The
enduring effects of abuse and related adverse
experiences in childhood. A convergence of
evidence from neurobiology and epidemiology." Eur
Arch Psychiatry Clin Neurosci 256(3)
174-86. Copeland, W. E., G. Keeler, et al.
(2007). "Traumatic events and posttraumatic
stress in childhood." Arch.Gen.Psychiatry 64(5)
577-584. Kendler, K. S., J. W. Kuhn, et al.
(2004). "Childhood sexual abuse, stressful life
events and risk for major depression in women."
Psychol.Med. 34(8) 1475-1482. Sroufe, L. A.
(2005). "Attachment and development a
prospective, longitudinal study from birth to
adulthood." Attach.Hum.Dev. 7(4) 349-367.
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1-2
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Criterion A Life Events