Differences in DPK Methods

1
Differences in DPK Methods
Utah/FDA
Franz
Area of Application 2x2 cm 1.12 cm diam Amount
Applied 20 ul 5 ul Area Stripped 2.5x5 cm 1.3
cm diam Tape Used Transpore (3M) D-Squame
(Cuderm)
2
Evaluation of Tretinoin Gels Experiment 10uL
of Avita, Retin-A and Tretinoin Gel were applied
to filter paper. Pictures were taken _at_ 2, 15, 30
and 60 minutes to evaluate the spreading of the
gels.
3
Tretinoin Gels _at_ 2 minutes
4
Tretinoin Gels _at_ 15 minutes
5
Tretinoin Gels _at_ 30 minutes
6
Tretinoin Gels _at_ 60 minutes