MyHeart Fighting Cardiovascular Diseases by Prevention and Early Diagnosis

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MyHeart Fighting Cardio-vascular Diseases by
Prevention and Early Diagnosis

• Ralf Schmidt, Jörg Habetha, Matthew Harris
• Philips Research Europe

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MyHeart Mission
Fighting Cardio-vascular Diseases by prevention
and early diagnosis

• Products services to effectively improve
  preventive life-style
• Solutions for disease (self-) management
• Safety security by ubiquitous access to
  premium care

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MyHeart Partners
Companies
Universities
Mind Media
Fondazione Centro San Raffaele
Lineapiù
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Why Cardio-vascular?
931.000 deaths in US are due to cardio-vascular
diseases 41 of all deaths
64 M US-citizen have a diagnosed heart
disease 22 of population

• Increasing Life-expectancy
• In 2025 more than 20 aged gt65 in EU, US and
  Japan (Source WHO)
• ?Aggravation of the Situation

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Framework for Personal Health MyHeart IST-e-hea
lth 6th framework Duration 45 Months Budget
35 M Funding 16 M (EU) Man Power 75
FTE Start 31.12.03 Partner 33 Project
coordination Philips Coordinator Joerg Habetha
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MyHearts Scope Application Matrix
Effects of population
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CardioActive
25
CardioSleep
40
CardioRelax
20
CardioBalance
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CardioSafe
Staying Healthy
Healthy at Risk
Post Event
Chronically Ill (AF, CHF,..)
Enabling life-long preventive and healthy
lifestyle!
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16 MyHeart Concepts

• Concept A Virtual Trainer
• Concept B Prevention Manager
• Concept C Outdoor Rehabilitation
• Concept D Sleep Care
• Concept E Stroke Rehabilitation
• Concept F Sleep Disorders
• Concept G Depression Management
• Concept H Stress Management
• Concept I Post Event Relaxation
• Concept J Obesity Management
• Concept K Myocardial Infarct Prevention
• Concept L Stroke Prevention
• Concept M Heart Failure Risk Monitor
• Concept N Hypoglycaemic Shock Prevention
• Concept O Post Intervention Follow Up
• Concept P Interactive Exercises

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MyHeart SystemClinical Excellence in hands of
citizen
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Technology Innovation
On-body electronics ? measure, diagnose, store
and communicate
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Some examples
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Some examples of working prototypes

• Smart bed
• For monitoring people unobstrusively during night

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MyHeart Phases
16 ideas

• Phase 1 Concept Jan/04-June/05 (18 months)
• Filling the application segmentation matrix
• building early demonstrators and mock-ups
• assessing customer/stakeholder reaction
• selecting the most attractive concepts
  business prop.
• Phase 2 Implementation July/05-June/06 (12
  months)
• realising the most attractive concepts
• defining reference architecture for prevention
• clinical/medical panel testing
• Phase 3 Validation July/06-Sep/07 (15 months)
• Demonstrating technical/medical feasibility
  (trials panels)
• Building partnerships for business exploitation
• Dissemination
• Sum 45 months

16 concepts
4 product concepts
1-4 field- tests
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MyHeart Product Concepts formed in June 2005

• For healthy people Activity Coach
• For people at risk Take Care
• For post event patients Neurological
  Rehabilitation
• For chronically ill patients Heart Failure
  Management

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MyHeart Scope Application Matrix
CardioActive
CardioSleep
CardioRelax
CardioBalance
CardioSafe
Staying Healthy
Healthy at Risk
Post Event
Chronically Ill (AF, CHF,..)
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MyHeart Scope
Health condition spectrum
preventative healthy living
living with chronic condition
Chronically Ill (AF, CHF,..)
Staying Healthy
Healthy at Risk
Post Event
Activity Coach
Neuro Rehab
Heart Failure Management
Take Care
Connected healthcare solutions On body monitoring
combined with feedback and interaction to various
stakeholders Empowering health well-being over
time Supporting care beyond the hospital
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Activity Coach Aim Relevance

• Aim
• End user value prop. Enjoy your regular exercise
  sessions, both in terms of pleasure and health
  impact, anywhere, anytime through personalized
  and motivating training programs
• Fitness Center value prop. It helps you to
  increase your sales and member retention by
  offering a personal trainer experience at lower
  cost
• Relevance
• Market fitness equipment 4.8 bln
• Market health clubs 35.9 bln

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Activity Coach Solution
Fitness Center
Personal Mobile Coach
Service Center
Info Booth
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Take Care Aim Relevance

• Aim
• Solution to self-manage CVD risk factors in daily
  life
• Assessment of CVD risk (WHO score tables)
• Easy-to-use technology indicating the health
  status and helping to improve it with
  personalized feedback and coaching
• Four value propositions sleep management, stress
  management, weight management, activity
  management
• Relevance
• High prevalence (25 insomnia, 40 stress, 50
  inactivity)
• Adopting a healthy lifestyle remarkably reduces
  the risk for developing CVD

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Example Sleep Module

• Aim Coaching people to improve sleep quality
• Solution System for monitoring vital parameters
  in bed

• Sensors
• Mechanical Piezo foil sensor system (below
  bed-sheet)
• Electrical Textile sheets in collaboration with
  MyHeart partners

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Neurological Rehabilitation Aim Relevance

• Aim
• Ensuring early intensive rehabilitation for more
  patients with neurological diseases, both
  inpatients and outpatients
• Improving care by innovative evidence-based
  treatments, able to quantify rehabilitation
  outcomes
• Addressing motor (upper limb) and cognitive
  (speech and reading) deficits
• Relevance
• 700000 events / year in US, 80 survive, only 25
  recover completely
• Re-imbursement of rehabilitation by insurance
  companies

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Catsuit For movement analysis
Textile solution hard-sensor system On-body
network 5 slave nodes (3acc, 3mag), 1 master
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Heart Failure Management

• Relevance
• 10 million patients in the EU are treated for
  Heart Failure
• Over 3bln hospitalization cost in the EU
• The cost of hospitalizations for HF is twice that
  for all forms of cancer and myocardial
  infarctions combined.
• Proper closed-loop management can reduce
  mortality significantly and has a cost-savings
  potential of several billion Euros world-wide.

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Heart Failure ManagementObjectives

• Early detection of cardiac decompensation
• Improve the management of chronic heart failure
• Prove the relevance of the daily monitored vital
  parameters for early detecting cardiac
  decompensation
• Show the usability and reliability of a system
  for daily home monitoring
• Include co-morbidities like arrhythmias and
  depression in HF management
• Provide physicians with relevant information for
  HF management
• Long-term
• Reduce mortality
• Reduce morbidity
• Increase quality of life
• Reduce hospitalisation costs

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We build a Heart Failure Management System and
test it in a Clinical Study
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Sensors Vital Signs
Sensor Vest
Smart Bed
Reference

• Weight
• Blood Pressure
• Implant
• ECG
• Activity

Respiration ECG Activity

• ECG
• Pressure
• Heart Rate
• Respiration Rate
• Activity

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Observational Study

• Primary Objective
• Determine if daily measurements of vital signs
  (heart rate, respiratory rate, impedance, blood
  pressure, arrhythmias, weight) obtained by the
  HFM system and the ICD devices predict cardiac
  decompensation.
• Secondary Objectives (selection)
• Usability and reliability of used technology
• Compare data from non-invasive sensors and
  implantable sensors (Optivol)
• 200 high risk HF patients (incomplete list of
  inclusion criteria)
• Hospital admisson due to HF for gt48h in last 12
  months
• Elevated BNP level at study inclusion
• ICD/CRT with Optivol feature (Medtronic implant
  with intra-thoracic impedance sensor)
• Study Design observational, prospective, open
  label, multi-center

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Conclusions Personal Healthcare

• Personal Healthcare will happen there is no
  alternative.
• Services are part of the solution.
• Technology follows application.
• Close partnership with the medical community is a
  must.

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