OER PPT

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http//www.nih.gov/
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http//www.grants.nih.gov/
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Getting Started OER Web Site
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Eligibility for NIH Funding

• In general, most NIH grants are available to
• Foreign institutions and international
  organizations
• Principal Investigators and other personnel who
  are not U.S. citizens
• Domestic organizations with a foreign component
• Note Exceptions are based on the type of
  program or grant (e.g., training and fellowships,
  small business awards, etc. are not eligible) and
  any specific eligibility requirements noted in a
  particular Funding Opportunity Announcement.

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NIH Grant Programs

• NIH funds grants, cooperative agreements, and
  contracts that support the advancement of
  fundamental knowledge about the nature and
  behavior of living systems to meet the NIH
  Mission.
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• Research Grants
• Career Development Awards
• Institutional Research Training Grants
• Fellowships
• Loan Repayment Awards
• Small Business Awards (SBIR/STTR)

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NIH OFFERS FUNDING PROGRAMS TO SUPPORT SCIENTISTS
AT EVERY STAGE OF THEIR CAREER
Approx. Stage of Research Training and Development
Mechanism of Support
Predoctoral Institutional Training Grant (T32)
GRADUATE/ MEDICAL STUDENT
Predoctoral Individual NRSA (F31) Predoctoral
Individual MD/PhD NRSA (F30)
Postdoctoral Institutional Training Grant (T32)
Postdoctoral Individual NRSA (F32)
POST DOCTORAL
NIH Pathway to Independence (PI) Award
(K99/R00) Mentored Research Scientist Development
Award (K01) Mentored Clinical Scientist
Development Award (K08) Mentored Patient-Oriented
RCDA (K23) Mentored Quantitative RCDA (K25)
EARLY
Small Grant (R03)
Research Project Grant (R01)
Independent Scientist Award (K02)
MIDDLE
CAREER
Midcareer Investigator Award in
Patient-Oriented Research (K24)
Exploratory/Development Grant (R21)
SENIOR
Senior Scientist Award (K05)
Graph represents a small sample of NIH funding
mechanisms available.
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http//grants.nih.gov/grants/funding/funding_progr
am.htm
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http//grants.nih.gov/grants/grants_process.htm
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How Does NIH Solicit Applications?(Exceptions
for Foreign Applicants Will be Noted)

• Federal Opportunity Announcements (FOA) published
  through
• the NIH Guide (http//grants.nih.gov/grants/guide/
  )
• at grants.gov

• Parent Announcements cover basic mechanisms
• investigator-initiated applications

• Special Opportunities to fill gaps
• Requests for Applications (RFA), a one-time call
  with set aside funds
• Program Announcement (PA) highlights areas of
  focus
• Program Announcement with Special Review (PAR)
  for special consideration and protected review
• Program Announcement with Set Aside (PAS)
  essentially,
  an RFA with multiple receipt dates
  

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http//www.grants.nih.gov/
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http//www.grants.nih.gov/
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Exceptions to Grants Process for Foreign
Applicants InvestigatorsCheck out the Foreign
Web Site
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FY2009 Foreign Funding Fun Facts

• Total Number of NIH Foreign Grants
• 628 Grant Awards
• 221 million
• What country receives the largest number of NIH
  foreign grants?
• Canada
• 192 Grants at 53.8 Million
• FYI
• 2nd in awards is the United Kingdom with 75
  grants
• 2nd in dollars is South Africa with 51.2 Million
• Six Canadian Provinces receive NIH grant funding

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FY2009 NIH Funding to Canada Approx. 54M
29.1M
10.8M
8.8M
4.5M
259.2
235.9
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FY2009 Award Types By Institution Quebec
Province
Types of Grants http//grants.nih.gov/grants/fun
ding/funding_program.htm
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FY2009 Top 3 Largest NIH Awards to Quebec
Province
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RePORT RePORTER (Formally known as
CRISP)Helping You Find Funded Research
Information Potential U.S. Collaborators
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http//www.grants.nih.gov/
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RePORT.NIH.GOV
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Click for FY2008 funded award information.
http//RePoRT.nih.gov (categorical spending
link) Annual support level for various
research, condition, and disease categories based
on grants, contracts, and other funding
mechanisms used across the National Institutes of
Health (NIH).
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• How can RePORT data help you?
• Who is already doing similar research local and
  abroad?
• Potential Collaborators?
• What type of research is being funded?
• Think of the possibilities!

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FY 2010 PLANS

• Customizable data books
• IC-specific RePORTs
• Interactive charts
• Explore integration with other databases (e.g.,
  clinicaltrials.gov)
• Analyze/chart/map/present search results
• Save favorites searches and portfolios
• Set alerts for new grants/publications/patents
• Export of RePORTER database as a bulk download
  and/or web service

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PEER REVIEW ENCHANCEMENTS
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Peer Review of Foreign Grant Applications

• Standard Review Criteria is used in evaluating
  and scoring applications from both Domestic and
  Foreign Institutions.
• Foreign Grant Applications also receive the
  following assessment
• Does the project present opportunities for
  furthering research programs in other countries
  that are not readily available in the U.S. or
  that augment existing U.S. resources?
• Does the proposed project have specific relevance
  to the mission and objectives of an Institute or
  Center and have the potential for significantly
  advancing the health sciences in the United
  States?

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Enhancing Peer Review
A Self-Study by the NIH in Partnership with the
Scientific Community to Strengthen Peer Review
in Changing Times Keeping the Goal in Mind
Fund the Best Science, by the Best Scientists,
with the Least Administrative Burden. NIH
Director, Dr. Elias A. Zerhouni
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Enhancing Peer ReviewSummary of Recommendations
More at http//enhancing-peer-review.nih.gov
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Enhancing Peer Review at NIHTimeline
Changes SO FAR
Changes NOW
January 2009
May/June 2009
January 2010 Submissions

• Alignment of
• applications
• review criteria
• Shorter
• Research Plans

• Phase out of
• A2 applications
• Identification of
• Early Stage Inv.
• applications

• Enhanced review
• criteria
• New scoring system
• Criterion scoring
• Structured critiques
• Clustering of New
• Inv. Applications
• Score order review

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EARLY STAGE NEW INVESTIGATORS
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NIH Exceeds New Investigator Goal
in FY 2008
FY 07 08 Target of 1,500 new R01
investigators
Note Used rolling avg. of past 5 years to set
new goals
R01-Equivalent awards include R01, R23, R29, and
R37 grants.
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New Investigator Definition

• New Investigator
• A Program Director or Principal Investigator
  (PD/PI) is considered a New Investigator if
  he/she has not previously competed successfully
  as a PD/PI for a significant independent NIH
  research grant (like an R01).
• Early Stage Investigator (ESI)
• A subset of New Investigators who are within 10
  years of receiving terminal degree or end of
  medical residency, whichever occurred most
  recently (requests for extension will be
  considered).

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HUMAN EMBRYONIC STEM CELLS
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Executive Order 13505 Removing Barriers to
Responsible Research Involving
Human Stem Cells March 9, 2009
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NIH Guidelines for Human
Stem Cell Research

• Effective July 7, 2009
• All hESCs must be
• Derived from embryos created by IVF for
  reproductive purposes and no longer needed for
  that purpose
• Donated by individuals who sought reproductive
  treatment and who gave voluntary written consent
  for human embryos to be used for research
  purposes

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Next Steps

• Applicants submit materials through an NIH
  webform http//stemcells.nih.gov/
• NIH staff conduct administrative reviews for
  Section IIA compliance
• ACD Working Group reviews other submissions ACD
  makes recommendations to NIH Director
• NIH Director makes final decisions for all hESCs
• Eligible lines listed on NIH Human Embryonic Stem
  Cell Registry

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FINANCIAL CONFLICT OF INTEREST(FCOI)
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NIH Oversight of Extramural
Financial Conflicts of
Interest

• Health Service (PHS) Regulation
• 42 CFR Part 50, Subpart F
• Responsibility for the identification and
  management of investigators FCOI is placed with
  the institution, which oversees the
  investigators activities.
• As the grantor agency, NIH has primary
  responsibility for overseeing institutional
  compliance with these requirements.
• Note Use of the eRA Commons FCOI
  module/reporting tool will be mandatory as of
  July 1, 2009 - NIH Guide Notice
  NOT-OD-09-072.html

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NIH has OversightInstitutions Manage
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FCOI Resources and Contacts

• Web Based Tutorial For Investigators
  http//grants.nih.gov/grants/policy/coi/tutorial/f
  coi.htm
• New Pilot New Pilot Program Announced for
  Reporting FCOI http//grants.nih.gov/grants/guid
  e/notice-files/NOT-OD-09-001.html
• Division of Grants Compliance and Oversight Home
  page with Updated FAQs http//grants.nih.gov/gran
  ts/compliance/compliance.htm
• Dedicated e-mail FCOIcompliance_at_mail.nih.gov

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ADDITIONAL RESOURCES
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OER Home Page Offers Valuable Links and Resources
http//grants.nih.gov
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Office of Extramural Research http//www.grants.ni
h.gov/
Subscribe today!
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Subscribe to the OER Nexus today! http//grants1.n
ih.gov/grants/nexus.htm
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Intramural Training Opportunities for
Foreign
Researchers at NIH

• Training opportunities at NIH are available for
  foreign national scientists through the NIH
  Visiting Program. More info at http//dis.ors.od.n
  ih.gov/visitingprogram/01_vpmain.html.
• The Visiting Program is open to scientists at all
  career levels. There are two categories of
  program participants
• Visiting Fellows who receive awards for research
  training
• Visiting Scientists who receive appointments to
  conduct research
• The NIH has long considered close interaction
  with foreign scientists in the conduct of
  collaborative research to be an essential
  ingredient in achieving its mission.

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OERs Value Is In Its Partnerships
OER
Applicant Institution
NIH
Authorized Institutional Official
Principal Investigator
Program Administrator
Review Administrator
Sponsored Research Administrator
Grants Management Administrator
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NIH and YOU! Building Partnerships in
Biomedical Behavioral Research!
The NIH supports research endeavors worldwide,
while providing opportunities for today and
tomorrows researchers to share their vision and
innovation. The future rests on your
ideas and
support of the process!
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NIH
Transforming medicine through discovery.