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Lupus criteria
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It is important to remember that a patient may have SLE ... Malar rash. Discoid lupus. Serositis. Oral ulcers. Arthritis. Photosensitivity. Blood abnormalities ... – PowerPoint PPT presentation
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Title: Lupus criteria
1
Lupus criteria
- For the purpose of identifying patients in
clinical studies, a person has SLE if 4 or more
of the 11 criteria are present, serially or
simultaneously, during any interval of
observation. - It is important to remember that a patient may
have SLE and not have 4 criteria.
2
Lupus criteria (pneumonic)
- M D S O A P B R A I N
3
Lupus criteria (pneumonic)
- M
- D
- S
- O
- A
- P
- B
- R
- A
- I
- N
4
Malarrash
5
Malarrash
6
Lupus criteria (pneumonic)
- M
- D
- S
- O
- A
- P
- B
- R
- A
- I
- N
7
Discoidrash
8
Discoidrash
9
Discoidrash
10
Lupus criteria (pneumonic)
- M
- D
- S
- O
- A
- P
- B
- R
- A
- I
- N
11
Lupus criteria (pneumonic)
- Serositis
- Pleuritis, pleural effusion
- Pericarditis, pericardial effusion
- Ascites
12
Lupus criteria (pneumonic)
- M
- D
- S
- O
- A
- P
- B
- R
- A
- I
- N
13
Oralulcers
14
Lupus criteria (pneumonic)
- M
- D
- S
- O
- A
- P
- B
- R
- A
- I
- N
15
Arthritis (with swelling)
16
Arthritis (Jaccouds)
17
Lupus criteria (pneumonic)
- M
- D
- S
- O
- A
- P
- B
- R
- A
- I
- N
18
Photosensitivity
19
Lupus criteria (pneumonic)
- M
- D
- S
- O
- A
- P
- B
- R
- A
- I
- N
20
Blood abnormalities
- Leukocytopenia (lt 4000 on 2 occasions)
- Lymphopenia (lt 1500 on 2 occasions)
- Hemolytic anemia
- Thrombocytopenia (lt100, 000)
21
Lupus criteria (pneumonic)
- M
- D
- S
- O
- A
- P
- B
- R
- A
- I
- N
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Renal A) Proteinuria (gt500 mg/24hrs) B)
Cellular casts
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Lupus criteria (pneumonic)
- M
- D
- S
- O
- A
- P
- B
- R
- A
- I
- N
24
Anti-nuclear antibodies (ANA)
Rim
Diffuse
Nucleolar
Speckled
25
Lupus pneumonic (criteria)
- M
- D
- S
- O
- A
- P
- B
- R
- A
- I
- N
26
Immune abnormalities
- Smith antibody
- Anti-ds DNA antibody
- Anti-phospholipid antibody (1997 modification)
- Anti-cardiolipin antibody (IgG or IgM)
- Biologic false positive VDRL (gt 6 months)
- Lupus anticoagulant
27
Lupus criteria (pneumonic)
- M
- D
- S
- O
- A
- P
- B
- R
- A
- I
- N
28
Neurologic A) Seizure
B) Psychosis
29
Lupus criteria (pneumonic)
- Malar rash
- Discoid lupus
- Serositis
- Oral ulcers
- Arthritis
- Photosensitivity
- Blood abnormalities
- Renal
- ANA
- Immune
- Neurologic
