RECOVERY OF BIOLOGICAL PRODUCTS

1
RECOVERY OF BIOLOGICAL PRODUCTS

• Conference Series

2
Subjects 1981 - 2001 initial steps, refolding
Number
Number
Extraction
Expanded/Fluidized beds
Number
Number
Cell lysis/disruption
Refolding
3
Subjects 1981 2001 unit operations
Number
Number
Membranes
Chromatography
Number
Number
Electro-separations
Membrane chromatography
4
Subjects 1981 2001 process modelling and
control
Number
Number
Modelling, control, automation
Analytical/On-line monitoring
5
Subjects 1981 2001 new chemistry
Number
Genetic solutions, tags Combinatorial chemistry
6
Subjects 1981 2001 transgenics, gene therapy
Number
Number
Transgenics
Gene therapy
7
Papers at R1, 1981 the inaugural year
Science and industry have come a long way to the
present, diversified array of expression and
production systems and from No approved
recombinant products in 1981 to 15 in 1991 to
around 100 approved products in 2001. Early
topics such as Recovery of low MW products such
as antibiotics, organic acids, and ethanol as
well as waste treatment have essentially disappear
ed from the Recovery series.
8
Papers at RX, 2001