SSME518 Instructional Technology and Material Development

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ENZYMES

• SSME-518Instructional Technology and Material
  Development
• Assignment2
• Presented by Harika
  Özge Kizilsu

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Outline

• Introduction to enzymes
• How enzyme work
• Activation energy
• Factors effecting enzyme activity
• Temperature
• pH
• Enzyme concentration
• Substrate concentration

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Introduction to enzymes

• Enzymes are usually proteins
• Enzymes are catalysts
• In general, names end with suffix ase

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Introduction to enzymes
3 x 1012 years is 500 times the age of the
earth!!!!
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Introduction to enzymes

• Enzymes
• increase the rate of a reaction
• not consumed by the reaction
• act repeatedly to increase the rate of reactions
• are often very specific for the substrate
• Reactants also called substrates of enzyme

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How enzyme work

• Enzymes physically interact with their substrates
• Substrates bind to the enzymes active site
• Enzyme reaction path

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How enzyme work

• Lock and Key Model

• Substrate fits into an active site perfectly.
• (key) (lock)

click to see animation of model
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How enzyme work

• Activation energy is
• the energy required to start a reaction.

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Factors effecting enzyme activity

• Temperature
• pH
• Enzyme concentration
• Substrate concentration

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Temperature
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pH
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Enzyme concentration
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Substrate concentration

• click to learn more

Enzyme concentration constant
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• ? Thank YOU ?

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References

• http//fig.cox.miami.edu/cmallery/255/255enz/enzy
  mology.htm
• http//ntri.tamuk.edu/cell/enzyme2.html
• http//www.animationfactory.com/animations/buildin
  gs/doors/6038e/