Storage and Handling Tips for Nanoparticles

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Storage and Handling Tips
for Nanoparticles
CD

• Storage
• Nanoparticles, nanomaterials, and nanopowders
  must always be stored in closed and sealed
  containers, and in cool and well-ventilated
  areas. If possible, it is best to use a
  laboratory cabinet restricted for storing
  nanomaterials only.
• All containers containing nanoparticles should be
  clearly identi?ed (e.g., Gold Nanoparticles). If
  the nanoparticles are received in a plastic bag
  provided by the supplier, the bag should be
  placed in a second hard-sealed container.
  Nanoparticles and nanopowders should be stored
  away from acids, oxidants, and other metals.
• Storage temperatures

Powders In solution
Ambient Temperature
Recommended in a dry place
Acceptable for brief periods during use
Acceptable
15 C
Recommended
Acceptable in a dry place
8 C
Recommended
Recommended
2 C
Gold (spheres, nanoshells, rods,
polystyrene) Silica shelled gold
Silver (spheres, plates, cubes) Silica shelled
silver
Silica, aminated silica, mesoporous silica
Dry powders
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• Expected shelf life

Expected Shelf Life
Silver (spheres) 2 months to over 1 year In Solution
Silica shelled gold 6 months to over 1 year In Solution
Silica shelled silver 6 months to over 1 year In Solution
Silica, aminated silica Over 1 year In Solution
Gold (spheres, nanoshells, rods) Over 1 year In Solution
Silver (plates, cubes) Over 1 year In Solution
Magnetite Over 1 year In Solution
All dry Powders Over 2 years

• Light exposure
• Keep silver nanoparticles away from light
  exposure other non-silver nanoparticles are okay
  to light
• exposure. However, please always follow speci?c
  storage requirements from products datasheet.
• Storage buffers
• Creative Diagnostics provides various types of
  nanoparticles in different storage buffer or as
  dry powders.
• In addition, custom buffers are also available
  upon our clients requests.

Nanopaticles
Storage Buffer
Magnetic Particles
Acetone, ddH2O, DI Water, DMSO, EDTA, Ethanol,
HCl, HEPES-NaOH, Hexane, Isopropanol, Isopropyl
Alcohol, methanol, PBS, Puri?ed Water, Sodium
Citrate, TE-Buffer, Tris
Silica Nanoparticles
Alcohol, DI Water, Ethanol, PBS, Tris, Water
Gold Nanoparticles
Acetone, Custom, DI Water, DMF, DMSO, Hexane,
Isopropanol, MES, Methanol, NaHCO3 Buffer, PBS,
SOBO, Sodium Borate, Sodium Citrate, Tris, Water
Silver Nanoparticles
DI Water, Ethanol, PBS, Sodium Citrate, Tris
Quantum Dots
Borate, Chloroform, Custom, DI Water,
Dichloromethane, Hexanes, Methanol, n-Hexane,
PBS, Toluene, Tris-HCl, Water
Polymer Nanoparticles
DI Water, DMSO, Ethanol, MES, Methanol, PBA, PBS,
Water
Upconverting Nanoparticles
Custom, Cyclohexane, DI Water, PBS
Titania Nanoparticles
1, 2-Propanediol, 2-Propanol, Ethylene Glycol,
Hexane, Water, Xylene
Graphene and Carbon Nanotube
DI water, Toluene, Water
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• Handling
• For nanoparticle colloids
• Shake each bottle before use. During storage,
  nanoparticles may settle to the bottom of the
  vial (especially nanoparticles with diametersgt
  30 nm). Before aliquoting or use, resuspend the
  precipitated nanoparticles by shaking the bottle
  vigorously until the solution is homogeneous.
  This usually requires a mixing time of about 30
  seconds. Visually inspect the bottom of the
  container to ensure no remaining settled
  particles.
• For nanoparticle powders
• It is recommended that the nanomaterials should
  be kept away from excessive moisture and humidity
  before they are ready for use or redispersed.
  Some nanopowders must be sealed under vacuum
  before use to limit exposure to air and
  moisture.
• It is recommended to wear double gloves.
• Table 1. Test results from mechanical
  deformations of gloves in the presence of
  nanoparticles

Gold (5 nm) Gold (50 nm) Silver (50 nm)
Nitrile (73 µm) Not recommended Fair Bad
Nitrile (117 µm) Fair Fair Fair
Nitrile (67 µm) Bad Bad Fair
Latex (123 µm) Fair Fair Fair
Neoprene (397 µm) Fair Fair Fair

• Do not open containers without proper isolation
  or air?ow.
• Make sure everyone in the laboratory is aware
  when you are working with nanoparticles.
• Disposal
• There are currently no speci?c regulations or
  guidelines for the proper disposal of
  nanoparticles. Therefore, it is important to
  handle nanoparticles very carefully because they
  are considered toxic. Any waste containing
  nanoparticles or nanomaterials should not be
  disposed in regular waste or washed down the
  drain. Nanoparticles should be disposed in
  accordance with the chemical waste guidelines of
  your laboratory or institution.
• All waste containers should be properly labeled
  to indicate that they contain nanoparticles and
  should be properly sealed once the container is
  full and ready to be discarded.
• If nanoparticles are in solution, explore
  pre-treatment options.

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• Quality Control
• When stored in the recommended manner, most
  nanoparticles are stable from 6 months to more
  than 1 year. Be sure to visually inspect the
  material before each use. If there are any
  visible ?oating particles in the solution, if
  the color of the solution changes, or if the
  color intensity decreases, the nanoparticles may
  have aggregated. At this time, these materials
  should be analyzed by UV-Visible spectroscopy,
  DLS, or TEM for quality veri?cation.
• Do not freeze. If the nanoparticles in the
  solution are frozen, the nanoparticles will
  irreversibly aggregate and the color of the
  solution may change.

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Address 45-1 Ramsey Road, Shirley, NY 11967, USA
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