Title: Tracking Birth Defects After Fertility Treatments
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Tracking Birth Defects After Fertility Treatments
2Tracking Birth Defects After Fertility Treatments
The study, which is published in the New England
Journal of Medicine, is one of the largest to
ever look at the relationship between fertility
treatments and birth defects. It linked 16 years
of data -- from 1986 to 2002 -- on
all infertility treatments at two clinics in
South Australia to a registry of more than
300,000 births and 18,000 birth defects.
Researcher Michael Davies, PhD, MPH, an associate
professor at the University of Adelaide in
Australia, declined to mention specific types of
defects, saying they are looking more deeply into
that in his forthcoming research.
Overall, the study found that the risk of any
birth defect in pregnancies involving assisted
conception was 8 compared with 6 in babies
conceived without?assisted techniques.
The risk of a birth defect after IVF was 7. The
rate of birth defects associated with ICSI was
higher at 10.
3For IVF, doctors mix a woman's eggs and the
male's sperm in a petri dish and later implant
these into the female. In ICSI, doctors inject a
single sperm directly into an egg to fertilize
it. Resulting embryos are then placed into a
woman's uterus or can be frozen for future
attempts.
4One important point When the doctors adjusted
their data to account for a host of medical
conditions and circumstances that are known to
raise the risk of birth defects, like the
mother's age and a history of smoking, the
increased risks associated with IVF largely went
away -- suggesting that the procedure itself was
not to blame.
5Birth defects associated with ICSI, however,
remained 55 higher than the rates seen in
fertile couples even after researchers took into
account underlying factors associated with birth
defects.
6Despite the apparent increased risk, "people
getting ICSI shouldn't be immediately alarmed,"
says Davies. "The newest data in the study are
now 10 years old, and in that time, there have
been dramatic improvements in implantation rates
in ICSI, which I take to mean that embryo quality
has improved over that time. So it could be that
we're looking at a historical snapshot and
technology has overtaken it somewhat," he says.
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9Get in touch CARE is a renowned pioneering
fertility centre. In the 10 years since we began,
we have helped many thousands of people become
parents. We can help you too CARE Womens
Centre 203, Vishal Astra, Satya SaiSquare,
Vijay Nagar, Indore Ph. 88890 16663 E
info_at_carewomenscentre.com
10 Contact us