CXCR4 knockout - PowerPoint PPT Presentation

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CXCR4 knockout

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CXCR6; chemokine (C-X-C motif) receptor 6; C-X-C chemokine receptor type 6; CXC-R6; CXCR-6; BONZO; STRL33; BB217514; CD186; TYMSTR; CDw186; G protein-coupled receptor; G-protein coupled receptor bonzo; G-protein coupled receptor STRL33 – PowerPoint PPT presentation

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Slides: 5
Provided by: biogene123

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Title: CXCR4 knockout


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Knockout Cell Line
  • CRISPR/Cas9 system consists of a guide RNA
    (gRNA) and a bacterial CRISPR-associated
    endonuclease (Cas9). The gRNA is a short
    synthetic RNA composed of a Cas9-binding
    scaffold sequence and 20 nucleotide
    targeting sequence that defines the target
    genomic site to be modified. Cas9 contains two
    nuclease domains to induce site-specific DNA
    cleavage. Its a scalable genome-wide editing
    technology for its ease of generating gRNAs. The
    simplicity and high-efficiency of CRISPR/Cas9
    system make it a preferable genomic knockout
    method to the traditional ZFN and TALEN system.
    Our scientists are experts at performing gene
    knockout with CRISPR/Cas9, from designing gRNA
    constructs to transfection and single clone
    generation of a wide range of cells, including
    difficult-to-transfect and tumor cell lines.

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Contact information
  • Provider Creative Biogene
  • URL https//www.creative-biogene.com/Services/Sta
    ble-cell-line-generation/Custom-Genome-Editing-Cel
    l-Lines.html
  • Address 45-1 Ramsey Road, Shirley, NY 11967, USA
  • Phone No. 1-631-619-7922
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