Title: Bone Cancer Treatment
1Bone Cancer Treatment
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america Snippet Bone cancer or bone marrow
cancer has many types and develops in various
ages of life. We have provided an elaborate
guide about bone cancer treatment, Symptoms,
causes, hospitals. Bone Cancer is a painful and
deadly disease. But this can be cured in early
stages easily. So this article provides you
information related to bone cancer, Signs or
symptoms of bone cancer, what may be the causes
of bone cancer, How often does it occur, what
treatment option do patients have, what are the
best hospitals for the bone cancer
treatment. What is bone cancer? Bone cancer is a
malignant (cancerous) tumor of the bone that
destroys normal bone tissue. All bone tumors are
not malignant. Benign (non-cancerous) bone tumors
are more common than malignant tumors. Malignant
and benign bone tumors can develop and compress
surrounding bone tissues, but when compared to
malignant tumors benign tumors do not spread, do
not destroy bone tissue, and rarely pose a
threat to life. Malignant tumors that start in
the bone tissue are called primary cancer of the
bones. Cancer that spreads to the bones of other
parts of the body, such as the prostate, breast
or lung, is called metastatic cancer and is
named after the organ or tissue in which it
began. Primary bone cancer is much less common
than cancer that spreads to the bones. How many
types of bone cancer exist?
2The bone cancer has different types, In this
article we have covered most common ones and
listed below. Osteosarcoma Osteosarcoma is the
most common type of bone cancer. Osteosarcoma
most commonly occurs in ages from 10 to 19, and
is more common in men. In young people,
osteosarcoma tends to develop at the ends of long
bones in areas where bone grows actively, often
around the knee, either at the end of the femur
(femur) or at the level of the tibia (tibia)
near knee. The next most common location for
bone cancer is in the arm bone. Even though, it
is possible that osteosarcoma develops in any
bone. Depending on the appearance of the tumor
cells under the microscope, there are also many
other subtypes of osteosarcoma. Chondrosarcoma Cho
ndrosarcoma is the second most common bone
cancer. It comes from cartilage cells attached
to or covering the bone. It is more common in
people over 40, and less than 5 of these
cancers occur in people under 20 years of age. It
can grow quickly and aggressively or develop
slowly. Chondrosarcoma is most commonly found in
the bones of the hips and pelvis. Ewing
sarcoma Ewing's sarcoma, sometimes called the
ESFT, is an aggressive form of bone cancer that
is most common in children aged 4 to 15 years. It
can occur in bones or soft tissues and is
thought to originate in primary nervous tissue.
These are more common among men than women. The
most common place for Ewing's sarcoma is the
middle part of the long bones of the arms and
legs. Pleomorphous Sarcoma (Malignant Fibrous
Histiocytoma) Of Bone Pleomorphic sarcoma is a
cancer formerly called malignant fibrous
histiocytoma or MFH. Pleomorphic sarcomas are
usually not bone cancers but soft tissues.
However, they can occur in the bone up to 5 of
cases. Pleomorphic sarcomas usually occur in
adults and can be found anywhere in the
body. Fibrosarcoma
3Fibrosarcoma is a rare type of bone cancer. It is
most often found behind the knee in
adults. Chordoma Chordoma is a very rare cancer
usually seen in people over 30 years old. It is
most often located in the lower or upper ends of
the spine. Signs Of Bone Cancer We have listed
common symptoms or signs of bone cancer.
Sometimes people with bone cancer do not have
any of these changes Or In some cases the cause
of a symptom may be a different medical
condition that is not cancer. When a bone tumor
develops, it presses on healthy bone tissue and
can destroy it, causing the following
symptoms Bone Pain. The first symptoms of bone
cancer are pain and swelling where the tumor is
located. The pain can come and go at the
beginning. Then it can become more severe and
more stable later. The pain may worsen with
movement, and there may be swelling in the
surrounding soft tissues. Swelling And Stiffness
Of The Joints A tumor that occurs near or in a
joint can cause swelling of the joint and become
tender or rigid. This means that a person can
have limited and painful range of
motion. Claudication If a bone with a tumor
breaks in one leg, it can lead to pronounced
lameness. Goiter is usually a symptom of advanced
bone cancer. Some other symptoms can be seen
rarely like weight loss, fever, general malaise,
and anemia, which is a low red blood cell
count. If you are concerned about the changes it
is advised to talk with your doctor. Your doctor
will ask you how long and how often you have
experienced the symptom, in addition to other
questions. This is to help them in diagnosis. If
cancer is diagnosed, symptom relief remains an
important part of cancer care and treatment. It
can also be called supportive care, symptom
management or
4palliative care. Be sure to talk to your health
care team about any symptoms you may have,
including any new symptoms or changes in
symptoms What Causes Bone Cancer There are many
factors can often influence cancer development,
but most of them do not directly cause cancer.
Some people with multiple risk factors never
develop cancer, while others have no known risk
factors for developing cancer. We have listed
below some of the factors that may increase the
chance of developing bone cancer Genetic
Osteosarcoma may develop in Children with
familial retinoblastoma (type of eye cancer).
People from families with a history of sarcomas
are observed with Li-Fraumeni syndrome, which
can lead them to osteosarcomas. Researchers are
discovering genes passed down from generation to
generation that increase the risk of developing
osteosarcoma compared to the general population.
All these conditions are rare. Previous
Radiotherapy Therapy People who have had
radiation treatment for other conditions have a
higher risk of developing bone cancer at the site
of radiation therapy. The majority of sarcomas
caused by radiotherapy include angiosarcoma and
soft tissue of the ASI or osteosarcoma. Chemothe
rapy Certain drugs, including anthracyclines and
alkylating agents, which are used in cancer
treatment may lead to developing a secondary
cancer like osteosarcoma. Benign Tumors Or Other
Bone Conditions Paget's disease of bone can lead
to osteosarcoma. Other non-cancerous bone
diseases may also increase the risk of
osteosarcoma. How often does bone cancer
occur? Primary bone cancer is rare. It accounts
for much less than 1 percent of all cancers.
Different types of bone cancer are more likely to
occur in certain populations
5Osteosarcoma most often occurs between 10 and 19
years of age. However, people over 40 who have
other conditions, such as Paget's disease (a
benign disease characterized by abnormal
development of new bone cells), have an
increased risk of developing this
cancer. Chondrosarcoma occurs mainly in the
elderly (over 40 years). The risk increases with
age. This disease rarely occurs in children and
adolescents. FHTs occur most often in children
and adolescents under 19 years of age. Boys are
more often affected than girls. These tumors are
extremely rare among African- American
children. Can Bone Cancer Be Cured? Yes. Bone
cancer is a curable disease in its early stages.
Just like other types of cancer this can be
cured in early stages easily. So please be aware
of symptoms of bone cancer and consult your
doctor. Bone Cancer Diagnosis In the process of
diagnosis the doctor may enquire about medical
history of patient and also family members. The
doctor conducts physical examination and can
order laboratory tests and other diagnostic
tests. Some of the tests are listed
below X-rays, which can show the shape, location
and size of a bone tumor. If X-rays suggest that
an abnormal area may be cancerous, the doctor
will probably ask for some other imaging tests.
The X-rays suggest that an abnormal area is
benign, but the doctor may want to do other
tests, especially if the patient experiences
unusual or persistent pain. Bone scintigraphy, a
test in which a small amount of radioactive
material is injected into a blood vessel and
passes through the bloodstream it then collects
in the bones and is detected by a scanner. A
scanner (CT or CAT), which is a series of
detailed images of areas inside the body, taken
from different angles, that are created by a
computer connected to an X-ray machine.
6A magnetic resonance imaging (MRI) procedure,
which useful in creating images of a particular
area inside the body without using X-rays. This
test gives detailed information that particular
area. This test uses a powerful magnet connected
to a computer to create detailed images. A
positron emission tomography (PET), In this test
a little amount of radioactive glucose is
injected into vein. Then computerized images were
collected by scanner which shows the usage of
glucose by cells in the tissue. If there is any
abnormal usage in the glucose indicates the
tumour. An angiogram (X-ray of the blood
vessels) Biopsy (taking a sample of tissue from
the bone tumor) to determine if the cancer is
present. The surgeon can perform an incisional
biopsy or a needle biopsy. During a needle
biopsy, the surgeon makes a small hole in the
bone and removes a tissue sample from the tumor
with a needle-shaped instrument. In an incisional
biopsy, the surgeon cuts into the tumor and
removes a part of tissue. Biopsies should be
performed by an orthopedic oncologist (a doctor
experienced in the treatment of bone cancer). A
pathologist (a doctor who identifies a disease by
studying cells and tissues under a microscope)
examines the tissue to determine if it is
cancerous. Blood tests to determine the level of
an enzyme called alkaline phosphatase. A huge
amount of this enzyme is present in the blood
when the cells that form the bone tissue are
very active - when the children grow up, when a
broken bone corrects itself or when a disease or
a tumor causes the production of abnormal bone
tissue . Since elevated levels of alkaline
phosphatase are normal in growing children and
adolescents, we cannot confirm bone cancer only
by thid test. What are the treatment options for
bone cancer? Treatment options depend on the
stage, location, size and type of the cancer,
along with them age, general health of the
person is also considered. There are four major
options available for treatment like cryosurgery,
radiotherapy, chemotherapy and surgery. Surgery
is most common option available for treatment.
The surgeon removes the entire tumor with
negative margins (no cancer cells are on the edge
or edge of
7tissue removed during surgery). The surgeon can
also use special surgical techniques to minimize
the amount of healthy tissue removed with the
tumor. Dramatic improvements in surgical
techniques and treatment of preoperative tumors
have allowed most bone cancer patients in an arm
or leg to avoid radical surgical procedures
(removal of the entire limb). However, most
patients who undergo limb-saving surgery require
reconstructive surgery to maximize limb
function. Chemotherapy is the use of anticancer
drugs to kill cancer cells. A combination of
anti-cancer drugs are usually given to bone
cancer patients. However, chemotherapy is not
currently used to treat chondrosarcoma. Radiation
therapy, involves the use of high-energy X-rays
to kill cancer cells. Surgical procedure and
radiation therapy are used combined in this
treatment. It is often used to treat
chondrosarcoma. It can also be used for patients
who refuse surgery. Cryosurgery is the use of
liquid nitrogen to freeze and kill cancer cells.
This type of treatment may be used instead of
conventional surgery to destroy the tumor. Which
specialists treat bone cancer? Bone cancer
patients are advised to visit medical oncologists
(for administration or chemotherapy) and
surgical oncologists or orthopedic oncologists
(for surgical removal of the tumor). Radiation
oncologists are involved in the treatment team if
radiotherapy is needed. Palliative care
physicians may be involved to manage pain and
symptoms. Is Bone Cancer Painful? Yes. Bone
Cancer is a painful disease. Analgesics
(analgesics) treat pain caused by bone cancer.
These may be over-the-counter or prescription
medications. Mild to moderate pain is treated
with drugs such as acetaminophen (Tylenol) or
nonsteroidal anti-inflammatory drugs, including
naproxen (Anaprox, Naprosyn, Aleve, Naprelan)
and ibuprofen (Motrin, Advil). However, people
taking cancer chemotherapeutic drugs may need to
avoid nonsteroidal anti-inflammatory drugs
because of an increased risk of bleeding.
8- Prescription drugs are used for moderate to
severe cancer pain. Opioids - more powerful
narcotic analgesics - such as fentanyl,
hydromorphone, morphine, oxycodone and codeine
may be needed to control severe pain. Sometimes a
combination of drugs is used to treat cancer
pain. Opioid medications may be associated with
side effects like constipation, nausea, and
drowsiness. - Is follow-up treatment necessary? What does this
imply? - Yes. Bone cancer sometimes metastasises,
especially in the lungs, or can reappear (come
back), either in the same place or in other bones
of the body. People who have had bone cancer
should consult their doctor regularly and report
any unusual symptoms immediately. Monitoring
varies for different types and stages of bone
cancer. Generally, patients are frequently
checked by their doctor and routinely undergo
X-rays and blood tests. People who have had bone
cancer, especially adolescents and children,
have an increased chance of developing another
type of cancer, like leukemia, later in life.
Regular follow-up care allows you to discuss
health changes and deal with problems as quickly
as possible - Best Bone Cancer Hospitals In India
- Best Bone Cancer Hospitals In Hyderabad
- American Oncology Institute
- The American Oncology Institute, the flagship
international center of CTSI (Cancer Treatment
Services International) based in the United
States, aims to bridge the gap between standards
of care in India and the United States. To do
this, they have transferred all the benefits of
the latest cancer treatments from the world's
most advanced countries to the people of India.
This ensures that all patients will receive care
at the level of what is available in the Western
world. - Address 1-100/1/CCH, Near aparna Sarovar,
Nallagandla, Serilingampally, Hyderabad,
Telangana 530019 - Phone 040 6719 9999
- Yashoda Cancer Institute
9- For two decades, the Yashoda Hospital Group has
been providing quality health care to people
with diverse medical needs. People trust this
hospital because of the strong relationships
they have built with their patients over the
years. - Address Old Malakpet, Nalgonda cross road,
Hyderabad, Telangana 500036 - Hours Open 24 hours
- Phone 040 4567 4567
- Best Bone Cancer Hospitals In New Delhi
- Dharamshila Narayana Superspeciality Hospital
- The Dharamshila Hospital and Research Center is
the first and only cancer hospital in India that
has been accredited by NABH. They also have NABH
accredation for all its allied specialties and
its laboratories. Dr. S. Khanna is the founder of
this hospital. - Address Vasundhara Enclave, Near New Ashok Nagar
Metro Station, Dallupura, New Delhi, Delhi
110096 - Hours Open 24 hours
- Phone 1860 208 0208
- Founded 1990
- Motto Cancer is Curable
- Dr Dinesh Bhurani, Hematologist In India, Bone
Marrow Transplant Specialist, Hematology Centre - The idea of Bone Marrow India was conceptualized
by Dr. Dinesh Bhurani, a prominent bone marrow
transplant specialist who has successfully
conducted approximately 400 bone marrow
transplants at the Rajiv Gandhi Cancer Institute
Research Center, New Delhi. There is a team of
five transplant specialists who provide
transplant care on your doorstep. - Address Rajiv Gandhi Cancer Institute Research
Centre,, Sector 5, Rohini, Near Rohini West
Metro Station, West Delhi, New Delhi, Delhi 110085
10- Phone 099715 00861.
- Best Bone Cancer Hospitals In Mumbai
- Tata Memorial Hospital
- Tata Memorial Hospital is located in Mumbai,
India. It is a specialized center for cancer
treatment and research, closely associated with
the Advanced Center for Cancer Education,
Treatment and Research. - Address Dr. E Borges Road, Parel, Mumbai,
Maharashtra 400012 - Hours Open 24 hours
- Phone 022 2417 7000
- Established February 28, 1941
- P.D. Hinduja Hospital Medical Research Centre
- The P.D. Hinduja National Hospital and Medical
Research Center is a multi- sectoral tertiary
care hospital. The Hinduja National Hospital and
the Medical Research Center were founded by
Parmanand Deepchand Hinduja. - Address Veer Sawarkar Marg, Mahim West, Mahim,
Mumbai, Maharashtra 400016 - Opening Hours 8AM
- Phone 022 6766 8181
- Number of beds 402
- Founded 1951
- Best Bone Cancer Hospitals In Bengaluru
- 1. Sri Shankara Cancer Hospital and Research
Center - The hospital provides expertise in all
super-specialties of cancer, has 42 highly
qualified and dedicated medical consultants. To
date, SSHRC has treated 21,000
11new cancer patients and has consistently sought
to achieve its primary goals of providing
affordable treatment, including free cancer
treatment. Address 1st Cross, Shankara Matt
Premises, Shankarapuram, Basavanagudi,
Bengaluru, Karnataka 560004 Hours Open 24
hours Phone 080 2698 1100 2. Kidwai Memorial
Institute of Oncology Kidwai Memorial Institute
of Oncology is a cancer care hospital located in
Bangalore, India. It is an autonomous institution
of the Karnataka government and a regional
cancer center funded by the Government of
India. Address KMIO Campus, Dr M H Mariagowda
Road, Near Bangalore Dairy, Bengaluru, Karnataka
560029 Phone 080 2609 4000 Established June 26,
1973 ss