Bullous Pemphigoid

1
Bullous Pemphigoid
2
Bullous Pemphigoid

• Bullous pemphigoid is a type of rare skin
  disorder that makes large, fluid-filled blisters
  on areas of skin that often flex like the lower
  abdomen, upper thighs or armpits. Bullous
  pemphigoid is most common in people who are older
  than age 60.Bullous pemphigoid happens when
  your immune system attacks a thin layer of tissue
  below your outer layer of skin. The reason for
  having this abnormal immune response is unknown,
  although it sometimes can be triggered by taking
  specific medications.Treatment generally
  includes corticosteroids, such as prednisone, and
  other drugs that suppress the immune system.
  Bullous pemphigoid can be life-threatening at
  times, especially for older people who are
  already in poor health.

3
Causes of bullous pemphigoid

• The cause of bullous pemphigoid is not well
  understood. The blisters occur because of a
  malfunction in the immune system.Your body's
  immune system normally produces antibodies to
  fight against bacteria, viruses or other
  potentially harmful foreign substances. For
  various reasons that are not clear, the body may
  develop an antibody to a particular tissue in
  your body. In bullous pemphigoid, the immune
  system produces antibodies to the skin's basement
  membrane, a thin layer of fibers connecting the
  outer layer of skin (epidermis) and the next
  layer of skin (dermis).

4
Causes of bullous pemphigoid
Continue

• ComplicationsIf torn blisters gets become
  infected, this can further lead to sepsis a
  potentially life-threatening infection that
  affects your entire body. This serious
  complication is more likely to occur in older
  adults who are in generally poor health.

5
Symptoms of Bullous Pemphigoid

• The prime impact of bullous pemphigoid is the
  appearance of large blisters that don't easily
  rupture when touched. The fluid inside the
  blisters is usually clear but may contain some
  blood. The skin around the blisters may appear
  normal or red.In most cases, the blisters are
  seen on the lower abdomen, groin, upper thighs
  and arms. Mostly, blisters are located along with
  the creases or folds present in the skin, like
  the skin on the inner side of a joint.The
  affected areas of skin can be very itchy. You
  might also develop blisters or sores in your
  mouth. Rarely, the mucous membranes which are
  present in the eyes can be involved, creating
  much redness, soreness and discomfort.

6
Treatment and Drugs for Bullous Pemphigoid

• The main focus of bullous pemphigoid treatment
  is to help the skin heal as quickly as possible
  and relieve itching. Your doctor will prescribe a
  combination of medicines that inhibit immune
  system activities that cause inflammation. These
  drugs may include CorticosteroidsThe most
  common treatment is prednisone, which comes in
  pill form. However, long-term use can increase
  your risk of weak bones, diabetes, high blood
  pressure, high cholesterol and cataracts.
  Corticosteroid ointment can be used on your
  affected skin and cause fewer side
  effects.Anti-inflammatoriesA variety of drugs
  with anti-inflammatory properties may be used
  alone or in combination with corticosteroids.
  Examples can be methotrexate (Trexall), a
  rheumatoid arthritis drug tetracycline, an
  antibiotic with anti-inflammatory properties and
  dapsone (Aczone), a leprosy treatment.

7
CONNECT WITH US

• Logon to
• www.lazoi.com
• Like us on Facebook
• https//www.facebook.com/LazoiTheLife
• Follow us on Twitter
• https//www.twitter.com/lazoithelife
• Follow us on Pinterest
• https//www.in.pinterest.com/lazoithelife