WELCOME

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WELCOME!

• Why Medical Imaging?
• Intro to CASILab
• Project on endovascular surgery
• What we do (and dont) expect from you

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Why Medical Imaging?
3D Graphics Computer Vision Image Processing
Registration Algorithms Mathematics Software/hard
ware
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Why Medical Imaging?
YOU have the potential to make an important
difference to many peoples lives in a way that
you can see immediately.
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CASILab Projectshttp//casilab.med.unc.edu/

• Vessel segmentation, graph description
• Tumor segmentation
• 3D image-guided surgery
• 3D image-guided endovascular surgery
• Analysis of vessel characteristics for disease
  diagnosis and staging
• Visualizations and graphics

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CASILab Project Contributors

• FACULTY STUDENTS
• Elizabeth Bullitt Marcel Prastawa (CS)
• Stephen Aylward Peter Lorenzen (CS)
• Guido Gerig Michael Rosenthal (CS)
• Sarang Joshi Damien Maupu (CS, visiting French
  student)
• Weili Lin Vijay Venkatraman (CS, ATT)
• Keith Smith Annie Bova (undergraduate)
• Stephen Pizer Tiffany Johnson (medical
  student)
• Henry Fuchs Inkjung Jung (Biostatistics)
• Mark Van Horn
• Andrei State
• Keith Muller

UNC Depts Surgery, Computer Science, Radiology,
Radiation Oncology, Biostatistics, Statistics KU
Leuven, Belgium.
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3D Image-Guided Endovascular Surgery

• What is endovascular surgery?
• TIPS project

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What is Endovascular Surgery?

• Open Surgery
• Advantages Easy to see, easier to deal with
  unexpected problems.
• Disadvantages large hole, longer recovery, tug
  and pull

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What is Endovascular Surgery?

• Endovascular Surgery
• Advantages small incision, no retraction.
• Disadvantages several, but a major disadvantage
  is the inability to visualize the path and target
  in 3D

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Endovascular Applications TIPS
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Endovascular Procedures TIPS
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TIPS Guidance Approach

• Preop segment 3D portal veins from CT
• Register (3D-2D) vessels with projection image
  pair
• Update registration by tracking a balloon on
  biplane projection images
• Track catheter on biplane images
• 3D stereo display with head tracking

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1. Vessel Segmentation
Aylward S, Bullitt E (2002) Initialization,
noise, singularities and scale in height ridge
traversal for tubular object centerline
extraction. IEEE-TMI 2161-75. Bullitt E,
Aylward S, Smith K, Mukherji S, Jiroutek M,
Muller K (2001) Symbolic Description of
Intracerebral Vessels Segmented from MRA and
Evaluation by Comparison with X-Ray Angiograms.
MedIA 5157-169.
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2. Initial Registration
Liu A, Bullitt E, Pizer SM (1998) 3D/2D
registration using tubular anatomical structures
as a basis. MICCAI 98, LNCS 1496 952-963.
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3. Registration Updates via Balloon Tracking
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4. Needle trackinghttp//casilab.med.unc.edu/need
letrack/needletrack.html
Real time needle tracking on pairs of projection
views. Given registration between the two views,
one can convert the needle into 3D and display
its relationship to the 3D target vessels.
Jolly B, Van Horn M, Aylward S, Bullitt E (2003)
Needle tracking and detection in the TIPS
endovascular procedure Accepted MICCAI
2003. Bullitt E, Liu A, Pizer SM (1997) Three
dimensional reconstruction of curves from
projection views. II. Analysis of error. Medical
Physics 241679-87.
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5. Visualization

• Illustration by Andrei State

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What Do We Expect From You?

• To take advantage of a multidisciplinary
  environment.
• To be productive and to have fun with it.

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What We Dont Expect From You

• 1. Instant perfection

2. To do drudge work.
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I Look Forward to Meeting You!
Demo/discussion 6-8 tonight in second floor hall
around the corner from G-Lab. Interviews Mon
afternoon. Elizabeth Bullitt.