BIOTECHNOLOGY IN LITHUANIA

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• BIOTECHNOLOGY IN LITHUANIA
• Brief overview

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GENERAL

• Business about 10 biotech companies
• (Traditional pharmaceutical companies, biomedical
  equipment (e.g. diagnostic instrumentation)
  producers are not regarded as biotechnological
  companies)
• Biotech research, basic and applied, - about 10
  institutions (universities, state research
  institutes, universities institutes)

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HISTORICAL

• 1970 Experimental Factory of Bulk Enzymes in
  Vilnius (went to bankrupt)
• 1975 All-Union Research Institute of Applied
  Enzymology, since 1992 Institute of
  Biotechnology (IBT)
• 1988 Biocentras UAB, IBT spin-off
• 1995 new spin-offs of IBT
• - Fermentas UAB
• - Biofa UAB, now Sicor Biotech UAB

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BUSINESS

• FERMENTAS UAB (www.fermentas.com)
• Molecular Tools Biodiagnostics
• Restriction enzymes
• DNA/RNA modifying enzymes
• PCR-related products
• Molecular biology kits
• Nucleotides
• Reagents
• More than 700 products, export 70 countries

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BUSINESS

• SICOR BIOTECH UAB (www.sicor.lt)
• Protein pharmaceuticals
• Interferon alfa-2b, human, recombinant
• Human growth hormone, recombinant
• Filgrastim human granulocyte-colony stimulating
  factor, recombinant
• Substances and dosage forms

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BUSINESS

• BIOCENTRAS UAB (www.biocentras.lt)
• Decontamination of environment
• Microbial compositions for decontamination of
  soil polluted by oil and oil products
• Microbial compositions for remediation of soil
  polluted by fats or grease
• Sorbents

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BUSINESS

• NEW COMPANIES
• SORPO UAB, 2000 Biodiagnostics (www.sorpo.com)
• BIOTECHPHARMA UAB, 2004 Protein pharmaceuticals
  (www.biotechpharma.lt)
• IMUNOLITA UAB, 2006 Cellular technologies for
  medical applications (www.imunolita.lt)
• PROFARMA UAB, 2007 - Protein pharmaceuticals
  (www.profarma.eu)

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BUSINESS

• BIOFUEL COMPANIES
• MESTILLA UAB Biodiesel (100 000 t/year)
  (www.mestilla.lt)
• RAPSOILA UAB Biodiesel (30 000 t/year)
  (www.rapsoila.lt)
• BIOFUTURE UAB Bioethanol (20 000 t/year)
  (www.biofuture.lt)

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RESEARCH

• INSTITUTE OF BIOTECHNOLOGY (www.ibt.lt)
• New multivalent vaccines, diagnostic tools, gene
  delivery systems
• Molecular mechanisms of restriction enzymes
• Structural and mechanistic studies of DNA and RNA
  methyltransferases
• Production and characterization of monoclonal
  antibodies
• Bioinformatics

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RESEARCH

• INSTITUTE OF BIOCHEMISTRY (www.bchi.lt)
• Basic research of oxidoreductases
• Development of biosensors, immunosensors and
  bioanalytical systems
• Search for new enzymatic activities and their
  application for synthesis of chemicals
• Bioanalytical applications of lipids with
  entrapped proteins

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RESEARCH

• INSTITUTE OF IMMUNOLOGY, VILNIUS UNIVERSITY
  (www.imi.lt)
• Design and lab. production of polyclonal and
  monoclonal antibodies
• Technologies for efficient drug and vaccine
  delivery
• Immunoanalysis, biosensors, immunosensors,
  nanotechnological methods

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RESEARCH

• AGROBIOTECHNOLOGY
• Lithuanian Institute of Agriculture (www.lzi.lt)
• Lithuanian Institute of Horticulture
  (www.lsdi.lt)
• Lithuanian Forest Research Institute (www.mi.lt)
• Lithuanian University of Agriculture (www.lzuu.lt)