Liver Function Test | A must needed precautionary act

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Title: Liver Function Test | A must needed precautionary act

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Liver Function Test

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Liver Function Test

Liver function test helps to determine the health
of your liver by measuring the level of proteins,
liver enzymes, or bilirubin in your blood.

3
When do you need a Liver Function Test???

If you have symptoms, to screen for any potential
liver problems or infections affecting the liver
such as hepatitis A, hepatitis B and hepatitis C.
To aid in the diagnosis of other conditions such
as gallstones.
When you have liver disease, to monitor the
progression and severity of the disease, and to
determine how well a treatment is working
To monitor side effects, if you are taking
prescription, or non-prescription medicines that
can affect your liver function.

4
Why do you need a Liver Function Test

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Common Tests for Liver Function Test

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Alanine Transaminase (SGPT)

Alanine Transaminase is used by your body to
metabolize protein
If the liver is damaged or not functioning
properly , Alanine Transaminase is released into
the blood.
This causes Alanine Transaminase levels to
increase.
A high result on this test can be sign of Liver
damage.
Doctor will prescribe you this test if you have
symptoms like Vomiting, Weakness, Extreme
tiredness, Dark-colored Urine, Itchy skin, or
Jaundice

7
Alkaline Phosphate

Alkaline Phosphate (ALP) is an enzyme found in
Bones, bile ducts and Liver.
An Alkaline Phosphate is typically ordered in
combination with several other tests.
High level of Alkaline Phosphate may indicate
liver damage, blockage of the bile ducts, or a
bone disease.
Children and adolescents may have elevated levels
of ALP because their bones are growing. Pregnancy
can also raise ALP levels.
Normal range for ALP Is (45 115) U/L .
Low levels of ALP can occur following a blood
transfusion or heart bypass surgery.
Low level of ALP can result from a zinc
deficiency or malnutrition.

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Aspartate aminotransferase (SGOT)

Aspartate aminotransferase is an enzyme found in
several parts of your body including , the heart,
liver and muscles.
Since Aspartate aminotransferase levels arent
specific for liver damage , its usually measured
together with Alanine Transferase to check
liver problems.
When liver is damaged , Aspartate transferase is
released into the bloodstream.
A high level of Aspartate aminotransferase test
might indicate a problem with liver or muscle.
The normal range for this test is 8-48 U/L.

9
Bilirubin test

Bilirubin is a waste product from breakdown of
red blood cells. Its ordinarily processed by
liver.
It passes through the liver before being excreted
through your stool.
A damaged liver cant properly process Bilirubin,
so this leads to an abnormally high level of
Bilirubin in the blood.
A high result on the bilirubin test indicates
that the liver isnt functioning properly
He normal range for bilirubin is 0.11.2 mg/dL
Indirect Bilirubin Bilirubin not attached to
glucuronic .
Total Bilirubin All the bilirubin in your blood
together. (0.3-1.9 mg/dL)

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Serum Albumin test

Albumin is the main protein made by your liver.
It performs many important bodily functions, Such
as
Stop fluid from leaking out of your blood vessels
.
Nourishes your tissues.
Transports hormones, vitamins and other
substances throughout your body.
An albumin test measures how well your liver is
making this particular protein. A low result on
this test indicates that your liver isnt
functioning properly.
The normal range for albumin is (3.55.0) grams
per deciliter (g/dL).

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Gamma-Glutamyl Transferase(GGT)

The Gamma-glutamyl tranferase test measures the
amount of enzyme in your blood.
Since enzymes are molecules that are necessary
for chemical reaction in your body, So
Gamma-glutamyl transferase functions in the body
as a transport molecule helping to move others
molecules around the body.
It plays a significant role in helping the liver
metabolize drugs other toxins.
This test being prescribed by doctor if he
suspects your liver damage due to heavy alcohol
use or any toxic substances like drugs / poison.

12
Serum Globulin test

Globulins are a group of proteins in your blood.
They are made in your liver by your immune
system. Globulins play an important role in liver
function, blood clotting, and fighting infection.
A total protein test may be included in a series
of tests to check how well your liver is working.
Globulin tests are blood tests. During a blood
test, a health care professional will take a
blood sample from a vein in your arm, using a
small needle.
Low globulin levels can be a sign of liver or
kidney disease.
High globulin levels may also indicate certain
types of cancer, such as multiple myeloma,
Hodgkin's disease.