Liver ExcisionCauterization

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Liver Excision-Cauterization

• Amine Hallab
• Kevin Mihelc, Jen Bacior, Hiroki Meguro
• Kelly Dympna MD, John Patzer PhDUniversity of
  Pittsburgh Senior Design-BioE 1161
• Tuesday January 18th, 2005

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Outline

• Background and Overview
• Design Proposal
• Responsibilities
• Achievements
• Future Work

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Background and Overview

• 1 in 10 Americans are or have been afflicted with
  liver disease
• Treatments Liver transplant
• Liver diseases are poorly understood
• Liver biopsy
• common procedure for afflicted liver diagnosis
• Essential tool for metabolic processes research
• American Liver Foundation 2003
• Maddrey, W C, Atlas of the Liver, 2004, Current
  Medicine Inc

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How do surgeons take a liver biopsy ?
- Fully excised pig liver - Picture taken by
Amine Hallab - BioScience Tower
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Design Proposal

• Liver Excision-Cauterization (LEC)
• LEC Functions
• To excise
• To cauterize
• To provide temperature control
• Thermal and electrical insulation
• Thermal and electrical conduction

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Personal Responsibilities

• External relations and scheduling
• Design history file revision
• Mathematical model
• Heat Transfer
• Structural design and materials
• Material selection
• Material structural analysis
• Animal testing

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Personal Achievements

• Good foundation on liver biopsy
• Met with mentors on monthly basis
• Design History File
• PDS, Object Tree Analysis, Function-Means
• Estimated heat model for structure and materials
  
• Stainless steal and Ceramic
• Thickness of materials
• Testing
• Certified for animal testing
• Provided a place for testing

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Future Work

• March
• Compute the math model
• for various parameters
• DHF revision
• April
• Final grant proposal
• Animal testing
• Final Presentation

• January
• Heat model for structural design purposes
• Prototyping prerequisites
• February
• Prototype process
• More calculation
• DHF revision

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Acknowledgments

• Mark Gartner, PhD
• Department of BioEngineering
• LEC Group
• Hiroki Meguro
• Kevin Mihelc
• Jen Bacior
• John Patzer, PhD
• Kelly Dympna, MD
• Stephan Safta and Richard Miller

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