A Community Affair

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A Community Affair
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HOWDY! Todd McDaniel President/CEO The Research
Valley Partnership
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There is no I in Team
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• Where we have been.
• Fall 2005 RVP hosts lunch with TAMU DeBakey
  Institute and TAMU BioEngineering
• A Vision is Hatched Could we have a World-Class
  Large Animal GLP facility in The Research Valley?
• A Big Sister to TIGM
• Who would need to be involved? What would the
  impact be? How do we make it a reality?
• A Visit with the Governors Office

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• Where we are Today.
• The Texas AM Institute for Preclinical Studies
  is now a reality.
• One of a kind in Texas
• The Team Approach is what made the project
  happen.

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TIPS Groundbreaking March 28th
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Why the Effort?
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The Research Valley Partnership

• A non-profit public-private economic development
  corporation
• Partners
• Brazos County, Cities of Bryan College Station
• Texas AM (ie Flagship, HSC, Agrilife Research,
  OTC)
• The Alliance (Private Sector)
• Programs Services Business Development and
  Innovation Economic Development

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Our Mission To be a catalyst for economic growth
in The Research Valley without regard to
municipal boundary, which engages higher
education and private industry in order to
achieve sustainable high quality economic
development success.
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Strategic Plan Goal 4 To focus significant
resources and planning activities that direct The
Research Valley on a course to become a
world-class health science/life science
community
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• Market Dynamics
• OTC Partner led the formulation of a Business
  Plan / Model (a Partner)
• US spend over 1 B / year in preclinical testing
• Market is dominated by a few players
• No Major Players in Texas or Region
• 500 medical device, biotech, drug discovery
  companies in Texas
• Few options for preclinical testing in Texas
  (especially large animal with spontaneous
  disease)
• RD and ETF exiting the State of Texas

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• Business Accelerator
• Currently NO life science business accelerator
  space in the Research Valley for emerging
  technology companies
• Unique opportunity to have life science emerging
  technology companies located at their
  research/lab site
• Stand Alone Project - 5M not including ongoing
  OM costs

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Economic Impact Perryman Analysis If Texas
achieves a concentration of this activity equal
to that of the US and becomes a typical state
with regard to these industries, gains of more
than 12,900 jobs in the College Station-Bryan
area and 131,700 in Texas could be expected as of
the tenth year. If Texas achieves a
concentration of this activity equal to that of
the Minnesota, a state with preclinical
capabilities which achieves a much greater
concentration of the related manufacturing
enterprises, the incremental jobs could be
expected are approximately 16,500 in the College
Station-Bryan area and almost 163,700 in Texas.
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Economic Impact Perryman Analysis Important
addition to the biotechnology complex in
Texas. LOCATED IN THE RESEARCH VALLEY!! The
TIPS project can lead to sizable economic
gains.The initiatives potential to serve as a
catalyst for development in key growth sectors is
event greater. TIPS IS A PROJECT WORTHY OF
SUBSTANTIAL SUPPORT.
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The Science behind it.
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• What is Good Laboratory Practices?
• FDA mandated research required to get a drug or
  device approved and into the marketplace
• The FDA Process (Discovery through Approval) has
  Key Hurdles/Stages

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• GOOD RESEARCH, NEEDED, UNIQUE
• Preclinical animal studies are a necessary part
  of drug and device development and Good
  Laboratory Practices (GLP) are required by the
  FDA for safety studies, prior to approval
• Improved, faster, and more effective methods to
  bring drugs and devices to the marketplace are
  needed to treat and prevent diseases.
• It presently takes 12 years and costs, on
  average, 1 billion dollars to bring a drug to the
  marketplace.

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• Why Texas AM, The Research Valley?
• States only College of Vet Medicine
• Spontaneous animal disease
• Substantial Tech Transfer/Commercialization push
  focused on medical device and drug development
• The States only large animal GLP Facility
• Geographical Central in the US and the Texas
  Triangle
• Provides supportive Infrastructure for Biotech
  industry

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• TIPS Vision.
• To become the leading facility to conduct
  comprehensive preclinical/GLP large animal
  studies that will improve the efficacy and
  efficiency of drug and device development by
• seamlessly integrating device and drug
  development from basic research/design to imaging
  and animal testing through human clinical trials
  in order to reduce the cost and improve the
  effectiveness of drug and device development

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The Deal.
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TIPS Funding Sources
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Community Investment Grant

• Asked to be a Partner (States Expectation)
• Cash Grant
• 500,000/year for 5 years
• Grant to be used to defray initial start-up costs
• 1st Pmt Due FY 08-09
• Consideration
• Start of TIPS operations by July 1, 2008
• New job creation in the Research Valley
• An investment of at least 26M in real and
  personal property
• RVP membership on TIPS Board of Directors
• Commitment to construct and maintain 10,000 sf of
  life science business accelerator offices to
  include wet lab space within the main building
• Commitment by TIPS to work with the RVP, on
  behalf of the community, to secure HS/LS emerging
  technology company tenants within said space

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Community Funding Partner Formula

• 3-2-1 Strategy over a 5-years Period
• City of College Station
• Fund 1/2 of Commitment 500,000/yr (1/2)
  250,000/yr
• Brazos County
• Fund 1/3 of Commitment 500,000/yr (1/3)
  166,000/yr
• City of Bryan
• Fund 1/6 of Commitment 500,000/yr (1/6)
  84,000/yr

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TIPS
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TIPS Site Plan
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TIPS Southwest View
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TIPS 1st Floor
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TIPS 2nd Floor
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• Current Status and Timeline?
• Operating in existing facilities
• Capacity issues
• Projects scheduled through early August
• Significant demand (DARPA)
• New Building
• February 2009 scheduled for animal housing
  occupancy
• May-June 2009 scheduled for full occupancy

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Final Thoughts.
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• A true community affair.
• No I in Team multiple partners involved in
  making TIPS a reality
• Buy in and support by both town and gown
• People create partnerships on behalf of the
  institutions they represent
• Project can serve as a catalyst to become THE
  RESEARCH VALLEY

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Interactive
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• The Opportunity A federal institution announces
  a 100 M program to be awarded to 4 universities
  across the nation. The purpose of this grant is
  to establish centers of excellence for taking
  biotech defense rd to the bed side.
• The Roles University (lead), community, state,
  federal, private representatives (group breakout)
  
• The Challenge Win the Grant!
• The Task Put together a one page Executive
  Summary detailing how and why you will win the
  grant.

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• Together. Moving Forward.

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