????????-Global Sales-2004

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????????-Global Sales-2004
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????????-Global Sales-2005
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????????-Therapy Leaders-2004
From IMS MIDAS, Dec 2004
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????????-Therapy Leaders-2005

• From IMS MIDAS, Dec 2005

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  ??????,2004?????????????3684???,??????????,2004???
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Drug Discovery Lead Generation
Gene
Genomics Protomics
5,000
Targets
Lead Generation
HTS
SAR
Lead optimization
Hit identification
Compounds From THMs
Drug candidates
ADME Toxicity
Safety/Efficacy
New Drugs
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Drug Development Process
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• Timeline 6 Years to 12 Years or Beyond
• ManPowers 3000 man years
• Cost US300 to 500 Million

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FDA approved drug
12-15 years 350-500 million
New Drug
3-6 years
5 1 years
3 years
Lead compounds 10,000
Clinical trials (I-III) 3-5
Pre-clinical 21
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2003?????????????
(1)
(2)
(3)
(4)

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  ?????152??,??2002???????????????????46???
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  pharmaceutical, medical technology, health care
  services products?(???290.54??8.52???)?
  (????EY)
• (4) 2003???NIH????270.66???? (????AAAS)

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